एगियोस फार्मास्यूटिकल्स, इंक.
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परिचय

यह पृष्ठ David P Schenkein के ज्ञात इनसाइडर व्यापार इतिहास का व्यापक विश्लेषण प्रदान करता है। इनसाइडर किसी कंपनी के अधिकारी, निदेशक या महत्वपूर्ण निवेशक होते हैं। इनसाइडर के लिए विशिष्ट, गैर-सार्वजनिक जानकारी के आधार पर अपनी कंपनियों में व्यापार करना गैरकानूनी है। इसका मतलब यह नहीं है कि उनके लिए अपनी कंपनियों में कोई भी व्यापार करना गैरकानूनी है। हालाँकि, उन्हें फॉर्म 4 के माध्यम से SEC को सभी ट्रेड्स की रिपोर्ट करनी होगी। इन प्रतिबंधों के बावजूद, अकादमिक शोध से पता चलता है कि इनसाइडर - सामान्य तौर पर - अपनी कंपनियों में बाजार से बेहतर प्रदर्शन करते हैं।

औसत व्यापार लाभप्रदता

औसत ट्रेड लाभप्रदता पिछले तीन वर्षों में इनसाइडर द्वारा की गई सभी खुले बाजार खरीद का औसत रिटर्न है। इसकी गणना करने के लिए, हम 10b5-1 ट्रेडिंग योजना के हिस्से के रूप में चिह्नित सभी ट्रेडों को छोड़कर, इनसाइडर द्वारा की गई प्रत्येक खुले बाजार, अनियोजित खरीदारी की जांच करते हैं। फिर हम 3, 6 और 12 महीनों में उन ट्रेडों के औसत प्रदर्शन की गणना करते हैं, प्रत्येक ट्रेड के लिए अंतिम प्रदर्शन मीट्रिक तैयार करने के लिए उनमें से प्रत्येक अवधि का औसत निकालते हैं। अंत में, हम इनसाइडर के लिए प्रदर्शन मीट्रिक की गणना करने के लिए सभी प्रदर्शन मीट्रिक का औसत निकालते हैं। इस सूची में केवल उन इनसाइडर को शामिल किया गया है जिन्होंने पिछले दो वर्षों में कम से कम तीन ट्रेड किए हैं।

यदि इस इनसाइडर ट्रेड की लाभप्रदता "N/A" है, तो इनसाइडर ने या तो पिछले तीन वर्षों में कोई खुले बाजार में खरीदारी नहीं की है, या उनके द्वारा किए गए व्यापार एक विश्वसनीय प्रदर्शन मीट्रिक की गणना करने के लिए बहुत हाल के हैं।

अपडेट फ्रीक्वेंसी: दैनिक

सर्वाधिक लाभदायक इनसाइडर व्यापारियों की सूची देखें।

उच्चतम रैंकिंग वाले इनसाइडर देखें
रिपोर्ट की गई इनसाइडर स्थिति वाली कंपनियाँ

SEC फाइलिंग से संकेत मिलता है कि David P Schenkein ने निम्नलिखित कंपनियों में होल्डिंग्स या ट्रेड्स की सूचना दी है:

प्रतिभूति टाइटल नवीनतम रिपोर्ट की गई होल्डिंग्स
US:DNLI / Denali Therapeutics Inc. Director 15,257
US:REGN / Regeneron Pharmaceuticals, Inc. Director 448
US:AGIO / Agios Pharmaceuticals, Inc. Director 126,242
US:BLUE / bluebird bio, Inc. Director 3,000
US:FMI / Foundation Medicine, Inc. Director 23,326
चार्ट को कैसे समझे

निम्नलिखित चार्ट David P Schenkein द्वारा किए गए प्रत्येक खुले-बाज़ार, गैर-योजनाबद्ध व्यापार के बाद प्रतिभूतियों के स्टॉक प्रदर्शन को दर्शाते हैं। गैर-योजनाबद्ध व्यापार वे व्यापार हैं जो 10b5-1 ट्रेडिंग योजना के हिस्से के रूप में नहीं किए गए थे। स्टॉक प्रदर्शन को शेयर मूल्य में संचयी प्रतिशत परिवर्तन के रूप में चार्ट किया गया है। उदाहरण के लिए, यदि कोई इनसाइडर व्यापार 1 जनवरी, 2019 को किया गया था, तो चार्ट आज तक प्रतिभूति में दैनिक प्रतिशत परिवर्तन दिखाएगा। यदि इस दौरान शेयर की कीमत $10 से $15 तक जाती है, तो शेयर की कीमत में संचयी प्रतिशत परिवर्तन 50% होगा। $10 से $20 तक की कीमत में परिवर्तन 100% होगा, और $10 से $5 की कीमत में परिवर्तन -50% होगा।

अंततः, हम यह निर्धारित करने का प्रयास कर रहे हैं कि इनसाइडर के व्यापार शेयर की कीमत में अतिरिक्त रिटर्न (सकारात्मक या नकारात्मक) से कितनी निकटता से संबंधित हैं, यह देखने के लिए कि क्या इनसाइडर, इनसाइडर जानकारी से लाभ के लिए अपने व्यापार का समय निर्धारित कर रहे हैं। उस स्थिति पर विचार करें जहां कोई इनसाइडर ऐसा कर रहा था। इस स्थिति में, हम या तो (a) खरीदारी के बाद सकारात्मक रिटर्न, या (a) बिक्री के बाद नकारात्मक रिटर्न की उम्मीद करेंगे। (a) के मामले में, खरीद चार्ट ऊपर की ओर झुके हुए वक्रों की एक श्रृंखला दिखाएगा, जो प्रत्येक खरीद लेनदेन के बाद सकारात्मक रिटर्न का संकेत देगा। (a) के मामले में, बिक्री चार्ट नीचे की ओर झुके हुए वक्रों की एक श्रृंखला दिखाएगा, जो प्रत्येक बिक्री लेनदेन के बाद नकारात्मक रिटर्न का संकेत देगा।

हालाँकि, केवल यह निष्कर्ष निकालने के लिए पर्याप्त नहीं है। यदि, उदाहरण के लिए, कंपनी का शेयर मूल्य कई वर्षों से गैर-चक्रीय चढ़ाई में था, तो हम उम्मीद करेंगे कि खरीद के बाद के सभी प्लॉट ऊपर की ओर झुके हुए होंगे। इसी तरह, कई वर्षों में गैर-चक्रीय गिरावट के परिणामस्वरूप व्यापार के बाद के प्लॉट नीचे की ओर झुकेंगे। इनमें से कोई भी चार्ट इनसाइडर व्यापार गतिविधि का सुझाव नहीं देगा।

सबसे मजबूत संकेतक वह स्थिति होगी जहां शेयर की कीमत बेहद चक्रीय थी, और खरीद चार्ट में सकारात्मक संकेत और बिक्री चार्ट पर नकारात्मक प्लॉट दोनों थे। यह स्थिति एक इनसाइडर के लिए अत्यधिक संकेत देने वाली होगी जो अपने वित्तीय लाभ के लिए ट्रेड्स का समय निर्धारित कर रहा था।

इनसाइडर खरीदारी AGIO / Agios Pharmaceuticals, Inc. - अल्पकालिक लाभ विश्लेषण

इस अनुभाग में, हम AGIO / Agios Pharmaceuticals, Inc. में की गई प्रत्येक अनियोजित, खुले बाज़ार की इनसाइडर खरीदारी की लाभप्रदता का विश्लेषण करते हैं। यह विश्लेषण यह समझने में मदद करता है कि क्या इनसाइडर लगातार असामान्य रिटर्न उत्पन्न करता है, और यह अनुसरण करने लायक है। यह विश्लेषण प्रत्येक व्यापार के बाद एक वर्ष के लिए है, और परिणाम सैद्धांतिक हैं।

निम्न तालिका सबसे हालिया खुले बाज़ार की खरीदारी को दर्शाती है जो स्वचालित ट्रेडिंग योजना का हिस्सा नहीं थी।

व्यापार की तिथि टिकर इनसाइडर रिपोर्ट किए गए
शेयर		 रिपोर्ट की गई
कीमत		 समायोजित
शेयर		 समायोजित
कीमत		 मूल लागत दिन
अधिकतम		 मूल्य
अधिकतम		 अधिकतम
लाभ ($)		 अधिकतम रिटर्न (%)
2019-11-13 AGIO Schenkein David P 8,064 31.0000 8,064 31.0000 249,984 250 55.9300 201,036 80.42

समायोजित कीमत विभाजित-समायोजित कीमत है। समायोजित शेयर विभाजित-समायोजित शेयर हैं।

AGIO / Agios Pharmaceuticals, Inc. Insider Trades
इनसाइडर बिक्री AGIO / Agios Pharmaceuticals, Inc. - अल्पकालिक हानि विश्लेषण

इस अनुभाग में, हम AGIO / Agios Pharmaceuticals, Inc. में की गई प्रत्येक अनियोजित, खुले बाज़ार की इनसाइडर बिक्री के अल्पकालिक नुकसान से बचने का विश्लेषण करते हैं। हानि से बचने का एक सुसंगत पैटर्न यह सुझाव दे सकता है कि भविष्य में बिक्री लेनदेन कीमत में गिरावट की भविष्यवाणी कर सकते हैं। यह विश्लेषण प्रत्येक व्यापार के बाद एक वर्ष के लिए है, और परिणाम सैद्धांतिक हैं।

निम्न तालिका सबसे हालिया खुले बाज़ार की बिक्री को दर्शाती है जो स्वचालित ट्रेडिंग योजना का हिस्सा नहीं थी।

व्यापार की तिथि टिकर इनसाइडर रिपोर्ट किए गए
शेयर		 रिपोर्ट की गई
कीमत		 समायोजित
शेयर		 समायोजित
कीमत		 मूल लागत दिन
न्यूनतम		 मूल्य
न्यूनतम		 अधिकतम हानि
बचाया ($)		 अधिकतम हानि
बचाया (%)
2024-02-27 AGIO Schenkein David P 11,858 33.6000 11,858 33.6000 398,429 38 27.5500 -71,740 -18.01
2024-02-27 AGIO Schenkein David P 57,471 34.8900 57,471 34.8900 2,005,163
2024-02-26 AGIO Schenkein David P 20,411 33.1900 20,411 33.1900 677,441
2024-02-23 AGIO Schenkein David P 47,731 33.0500 47,731 33.0500 1,577,510

समायोजित कीमत विभाजित-समायोजित कीमत है। समायोजित शेयर विभाजित-समायोजित शेयर हैं।

AGIO / Agios Pharmaceuticals, Inc. Insider Trades
इनसाइडर व्यापार इतिहास

यह तालिका सिक्योरिटीज एक्सचेंज कमीशन (SEC) को बताए अनुसार David P Schenkein द्वारा किए गए इनसाइडर व्यापारों की पूरी सूची दिखाती है।

फ़ाइल तिथि ट्रांजेक्शन तिथि फॉर्म टिकर प्रतिभूति कोड 10b5-1 शेयर शेष शेयर प्रतिशत
परिवर्तन		 शेयर
कीमत		 ट्रांजेक्शन
वैल्यू		 शेष
मूल्य
2025-06-05 2025-06-03 4 DNLI Denali Therapeutics Inc.
Common Stock 		A - Award 6,037 15,257 65.48
2025-01-06 2025-01-02 4 REGN REGENERON PHARMACEUTICALS, INC.
Common Stock 		A - Award 166 448 58.87
2024-11-13 2024-11-11 4 DNLI Denali Therapeutics Inc.
Common Stock 		S - Sale X -32,312 9,220 -77.80 32.87 -1,062,095 303,061
2024-11-13 2024-11-11 4 DNLI Denali Therapeutics Inc.
Common Stock 		S - Sale X -27,129 41,532 -39.51 32.09 -870,570 1,332,762
2024-11-13 2024-11-11 4 DNLI Denali Therapeutics Inc.
Common Stock 		M - Exercise 47,165 68,661 219.41 18.00 848,970 1,235,898
2024-06-17 2024-06-13 4 AGIO AGIOS PHARMACEUTICALS, INC.
Common stock 		M - Exercise 3,388 126,242 2.76
2024-06-04 2024-05-31 4 DNLI Denali Therapeutics Inc.
Common Stock 		A - Award 5,967 21,496 38.42
2024-02-29 2024-02-27 4 AGIO AGIOS PHARMACEUTICALS, INC.
Common stock 		S - Sale -57,471 122,854 -31.87 34.89 -2,005,163 4,286,376
2024-02-29 2024-02-27 4 AGIO AGIOS PHARMACEUTICALS, INC.
Common stock 		M - Exercise 57,471 180,325 46.78 31.64 1,818,382 5,705,483
2024-02-29 2024-02-27 4 AGIO AGIOS PHARMACEUTICALS, INC.
Common stock 		S - Sale -11,858 122,854 -8.80 33.60 -398,429 4,127,894
2024-02-29 2024-02-27 4 AGIO AGIOS PHARMACEUTICALS, INC.
Common stock 		M - Exercise 11,858 134,712 9.65 31.64 375,187 4,262,288
2024-02-27 2024-02-26 4 AGIO AGIOS PHARMACEUTICALS, INC.
Common stock 		S - Sale -20,411 122,854 -14.25 33.19 -677,441 4,077,524
2024-02-27 2024-02-26 4 AGIO AGIOS PHARMACEUTICALS, INC.
Common stock 		M - Exercise 20,411 143,265 16.61 31.64 645,804 4,532,905
2024-02-27 2024-02-23 4 AGIO AGIOS PHARMACEUTICALS, INC.
Common stock 		S - Sale -47,731 122,854 -27.98 33.05 -1,577,510 4,060,325
2024-02-27 2024-02-23 4 AGIO AGIOS PHARMACEUTICALS, INC.
Common stock 		M - Exercise 47,731 170,585 38.85 31.64 1,510,209 5,397,309
2024-01-04 2024-01-02 4 REGN REGENERON PHARMACEUTICALS, INC.
Common Stock 		A - Award 42 282 17.50
2023-09-12 2023-09-08 4 REGN REGENERON PHARMACEUTICALS, INC.
Common Stock 		A - Award 240 240
2023-06-23 2023-06-21 4 AGIO AGIOS PHARMACEUTICALS, INC.
Common stock 		M - Exercise 4,975 122,854 4.22
2023-06-05 2023-06-01 4 DNLI Denali Therapeutics Inc.
Common Stock 		A - Award 4,216 15,529 37.27
2023-04-05 2023-04-03 4 AGIO AGIOS PHARMACEUTICALS, INC.
Common stock 		S - Sale X -16,363 117,879 -12.19 22.85 -373,895 2,693,535
2023-04-05 2023-04-03 4 AGIO AGIOS PHARMACEUTICALS, INC.
Common stock 		M - Exercise X 16,363 134,242 13.88 9.05 148,085 1,214,890
2023-03-29 2023-03-27 4 AGIO AGIOS PHARMACEUTICALS, INC.
Common stock 		S - Sale X -20,000 117,879 -14.51 22.15 -443,000 2,611,020
2023-03-29 2023-03-27 4 AGIO AGIOS PHARMACEUTICALS, INC.
Common stock 		M - Exercise X 20,000 137,879 16.97 9.05 181,000 1,247,805
2023-03-15 2023-03-13 4 AGIO AGIOS PHARMACEUTICALS, INC.
Common stock 		S - Sale X -1,667 117,879 -1.39 22.72 -37,874 2,678,211
2023-03-15 2023-03-13 4 AGIO AGIOS PHARMACEUTICALS, INC.
Common stock 		S - Sale X -18,333 119,546 -13.30 22.47 -411,943 2,686,199
2023-03-15 2023-03-13 4 AGIO AGIOS PHARMACEUTICALS, INC.
Common stock 		M - Exercise X 20,000 137,879 16.97 9.05 181,000 1,247,805
2023-03-01 2023-02-27 4 AGIO AGIOS PHARMACEUTICALS, INC.
Common stock 		S - Sale X -20,000 117,879 -14.51 25.37 -507,400 2,990,590
2023-03-01 2023-02-27 4 AGIO AGIOS PHARMACEUTICALS, INC.
Common stock 		M - Exercise X 20,000 137,879 16.97 9.05 181,000 1,247,805
2023-02-15 2023-02-13 4 AGIO AGIOS PHARMACEUTICALS, INC.
Common stock 		S - Sale X -20,000 117,879 -14.51 28.62 -572,400 3,373,697
2023-02-15 2023-02-13 4 AGIO AGIOS PHARMACEUTICALS, INC.
Common stock 		M - Exercise X 20,000 137,879 16.97 9.05 181,000 1,247,805
2023-02-01 2023-01-30 4 AGIO AGIOS PHARMACEUTICALS, INC.
Common stock 		S - Sale X -3,300 117,879 -2.72 29.88 -98,604 3,522,225
2023-02-01 2023-01-30 4 AGIO AGIOS PHARMACEUTICALS, INC.
Common stock 		S - Sale X -16,700 121,179 -12.11 29.22 -487,974 3,540,850
2023-02-01 2023-01-30 4 AGIO AGIOS PHARMACEUTICALS, INC.
Common stock 		M - Exercise X 20,000 137,879 16.97 9.05 181,000 1,247,805
2023-01-19 2023-01-17 4 AGIO AGIOS PHARMACEUTICALS, INC.
Common stock 		S - Sale X -1,034 117,879 -0.87 29.49 -30,493 3,476,252
2023-01-19 2023-01-17 4 AGIO AGIOS PHARMACEUTICALS, INC.
Common stock 		S - Sale X -18,966 118,913 -13.76 28.82 -546,600 3,427,073
2023-01-19 2023-01-17 4 AGIO AGIOS PHARMACEUTICALS, INC.
Common stock 		M - Exercise X 20,000 137,879 16.97 9.05 181,000 1,247,805
2022-06-06 2022-06-02 4 DNLI Denali Therapeutics Inc.
Common Stock 		A - Award 5,986 11,313 112.37
2022-05-24 2022-05-20 4 AGIO AGIOS PHARMACEUTICALS, INC.
Restricted stock unit 		M - Exercise -1,585 0 -100.00
2022-05-24 2022-05-20 4 AGIO AGIOS PHARMACEUTICALS, INC.
Common stock 		M - Exercise 1,585 117,879 1.36
2022-02-23 2022-02-22 4 AGIO AGIOS PHARMACEUTICALS, INC.
Restricted stock units 		M - Exercise -2,775 0 -100.00
2022-02-23 2022-02-22 4 AGIO AGIOS PHARMACEUTICALS, INC.
Common stock 		F - Taxes -758 116,294 -0.65 29.08 -22,043 3,381,830
2022-02-23 2022-02-22 4 AGIO AGIOS PHARMACEUTICALS, INC.
Common stock 		M - Exercise 2,775 117,052 2.43
2021-06-04 2021-06-02 4 DNLI Denali Therapeutics Inc.
Stock Option (right to buy) 		A - Award 6,222 6,222
2021-06-04 2021-06-02 4 DNLI Denali Therapeutics Inc.
Common Stock 		A - Award 2,074 5,327 63.76
2021-06-03 2021-06-01 4 DNLI Denali Therapeutics Inc.
Restricted Stock Units 		M - Exercise -3,253 0 -100.00
2021-06-03 2021-06-01 4 DNLI Denali Therapeutics Inc.
Common Stock 		M - Exercise 3,253 3,253
2021-06-02 2021-05-28 4 AGIO AGIOS PHARMACEUTICALS, INC.
Restricted stock units 		M - Exercise -1,686 0 -100.00
2021-06-02 2021-05-28 4 AGIO AGIOS PHARMACEUTICALS, INC.
Common stock 		M - Exercise 1,686 114,277 1.50
2021-05-24 2021-05-20 4 AGIO AGIOS PHARMACEUTICALS, INC.
Stock options (right to buy) 		A - Award 8,888 8,888
2021-05-24 2021-05-20 4 AGIO AGIOS PHARMACEUTICALS, INC.
Restricted stock unit 		A - Award 1,585 1,585
2021-02-24 2021-02-22 4 AGIO AGIOS PHARMACEUTICALS, INC.
Restricted stock units 		M - Exercise -2,774 2,775 -49.99
2021-02-24 2021-02-22 4 AGIO AGIOS PHARMACEUTICALS, INC.
Common stock 		F - Taxes -821 112,591 -0.72
2021-02-24 2021-02-22 4 AGIO AGIOS PHARMACEUTICALS, INC.
Common stock 		M - Exercise 2,774 113,412 2.51
2021-02-17 2021-02-16 4 AGIO AGIOS PHARMACEUTICALS, INC.
Restricted stock units 		M - Exercise -8,125 0 -100.00
2021-02-17 2021-02-16 4 AGIO AGIOS PHARMACEUTICALS, INC.
Common stock 		F - Taxes -2,540 110,638 -2.24
2021-02-17 2021-02-16 4 AGIO AGIOS PHARMACEUTICALS, INC.
Common stock 		M - Exercise 8,125 113,178 7.73
2020-12-23 2020-12-21 4 DNLI Denali Therapeutics Inc.
Common Stock 		S - Sale X -5,000 26,232 -16.01 90.01 -450,027 2,361,022
2020-12-23 2020-12-21 4 DNLI Denali Therapeutics Inc.
Common Stock 		S - Sale X -25,000 0 -100.00 90.06 -2,251,555
2020-11-13 2020-11-12 4 DNLI Denali Therapeutics Inc.
Common Stock 		S - Sale X -30,000 25,000 -54.55 70.05 -2,101,590 1,751,325
2020-11-12 2020-11-10 4 DNLI Denali Therapeutics Inc.
Common Stock 		S - Sale X -10,000 55,000 -15.38 60.03 -600,310 3,301,705
2020-11-06 2020-11-04 4 DNLI Denali Therapeutics Inc.
Common Stock 		S - Sale X -10,000 65,000 -13.33 50.18 -501,830 3,261,895
2020-06-22 2020-06-18 4 BLUE bluebird bio, Inc.
Stock Option (right to buy) 		A - Award 3,000 3,000
2020-06-22 2020-06-18 4 BLUE bluebird bio, Inc.
Common Stock 		A - Award 1,500 6,832 28.13
2020-06-22 2020-06-18 4 BLUE bluebird bio, Inc.
Common Stock 		A - Award 156 5,332 3.01
2020-06-05 2020-06-03 4 DNLI Denali Therapeutics Inc.
Restricted Stock Units 		A - Award 3,253 3,253
2020-06-05 2020-06-03 4 DNLI Denali Therapeutics Inc.
Stock Option (right to buy) 		A - Award 15,183 15,183
2020-06-01 2020-05-28 4 AGIO AGIOS PHARMACEUTICALS, INC.
Restricted stock units 		A - Award 1,686 1,686
2020-06-01 2020-05-28 4 AGIO AGIOS PHARMACEUTICALS, INC.
Stock options (right to buy) 		A - Award 8,096 8,096
2020-02-25 2020-02-24 4 AGIO AGIOS PHARMACEUTICALS, INC.
Common stock 		F - Taxes -880 105,053 -0.83 48.66 -42,821 5,111,879
2020-02-25 2020-02-22 4 AGIO AGIOS PHARMACEUTICALS, INC.
Restricted stock units 		M - Exercise -2,775 5,549 -33.34
2020-02-25 2020-02-22 4 AGIO AGIOS PHARMACEUTICALS, INC.
Common stock 		M - Exercise 2,775 105,933 2.69
2020-02-19 2020-02-18 4 AGIO AGIOS PHARMACEUTICALS, INC.
Common stock 		F - Taxes -2,534 103,158 -2.40 52.01 -131,793 5,365,248
2020-02-19 2020-02-16 4 AGIO AGIOS PHARMACEUTICALS, INC.
Restricted stock units 		M - Exercise -8,125 8,125 -50.00
2020-02-19 2020-02-16 4 AGIO AGIOS PHARMACEUTICALS, INC.
Common stock 		M - Exercise 8,125 105,692 8.33
2019-11-15 2019-11-13 4 AGIO AGIOS PHARMACEUTICALS, INC.
Common stock 		P - Purchase 8,064 97,567 9.01 31.00 249,984 3,024,577
2019-06-10 2019-06-06 4 BLUE bluebird bio, Inc.
Stock Option (right to buy) 		A - Award 4,000 4,000
2019-06-10 2019-06-06 4 BLUE bluebird bio, Inc.
Common Stock 		A - Award 1,000 5,176 23.95
2019-06-03 2019-05-30 4 DNLI Denali Therapeutics Inc.
Stock Option (right to buy) 		A - Award 27,245 27,245
2019-02-26 2019-02-22 4 AGIO AGIOS PHARMACEUTICALS INC
Restricted stock units 		A - Award 8,324 8,324
2019-02-26 2019-02-22 4 AGIO AGIOS PHARMACEUTICALS INC
Stock option (right to buy) 		A - Award 45,719 45,719
2019-02-20 2019-02-19 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		F - Taxes -2,471 89,503 -2.69 58.03 -143,392 5,193,859
2019-02-20 2019-02-16 4 AGIO AGIOS PHARMACEUTICALS INC
Restricted stock units 		M - Exercise -8,125 16,250 -33.33
2019-02-20 2019-02-16 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		M - Exercise 8,125 91,974 9.69
2018-11-19 2018-11-08 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		G - Gift -1,000 270,772 -0.37
2018-09-12 2018-09-10 4 AGIO AGIOS PHARMACEUTICALS INC
Stock option (right to buy) 		M - Exercise -8,730 137,471 -5.97
2018-09-12 2018-09-10 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		M - Exercise 8,730 83,849 11.62 31.64 276,217 2,652,982
2018-09-07 2018-09-05 4 AGIO AGIOS PHARMACEUTICALS INC
Stock option (right to buy) 		M - Exercise -2,500 146,201 -1.68
2018-09-07 2018-09-05 4 AGIO AGIOS PHARMACEUTICALS INC
Stock option (right to buy) 		M - Exercise -72,619 0 -100.00
2018-09-07 2018-09-05 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		M - Exercise 2,500 75,119 3.44 31.64 79,100 2,376,765
2018-09-07 2018-09-05 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		M - Exercise 72,619 72,619 2.34 169,928 169,928
2018-06-22 2018-06-20 4 BLUE bluebird bio, Inc.
Stock Option (right to buy) 		A - Award 4,000 4,000
2018-06-22 2018-06-20 4 BLUE bluebird bio, Inc.
Common Stock 		A - Award 1,000 4,176 31.49
2018-06-15 2018-06-13 4 DNLI Denali Therapeutics Inc.
Stock Option (right to buy) 		A - Award 27,830 27,830
2018-06-05 2018-06-01 4 AGIO AGIOS PHARMACEUTICALS INC
Stock option (right to buy) 		M - Exercise X -108 72,619 -0.15
2018-06-05 2018-06-01 4 AGIO AGIOS PHARMACEUTICALS INC
Stock option (right to buy) 		M - Exercise X -12,892 0 -100.00
2018-06-05 2018-06-01 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -100 0 -100.00 96.91 -9,691
2018-06-05 2018-06-01 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -3,190 100 -96.96 96.40 -307,516 9,640
2018-06-05 2018-06-01 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -8,200 3,290 -71.37 95.11 -779,902 312,912
2018-06-05 2018-06-01 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -1,510 11,490 -11.62 94.37 -142,499 1,084,311
2018-06-05 2018-06-01 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		M - Exercise X 108 13,000 0.84 2.34 253 30,420
2018-06-05 2018-06-01 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		M - Exercise X 12,892 12,892 0.47 6,027 6,027
2018-06-01 2018-05-30 4 AGIO AGIOS PHARMACEUTICALS INC
Stock option (right to buy) 		M - Exercise X -23,471 12,892 -64.55
2018-06-01 2018-05-30 4 AGIO AGIOS PHARMACEUTICALS INC
Stock option (right to buy) 		M - Exercise X -16,193 0 -100.00
2018-06-01 2018-05-30 4 AGIO AGIOS PHARMACEUTICALS INC
Stock option (right to buy) 		M - Exercise X -5,962 0 -100.00
2018-06-01 2018-05-30 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -45,626 0 -100.00 90.07 -4,109,534
2018-06-01 2018-05-30 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		M - Exercise X 23,471 45,626 105.94 0.47 10,973 21,330
2018-06-01 2018-05-30 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		M - Exercise X 16,193 22,155 271.60 0.30 4,898 6,702
2018-06-01 2018-05-30 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		M - Exercise X 5,962 5,962 0.30 1,804 1,804
2018-05-29 2018-05-23 4 AGIO AGIOS PHARMACEUTICALS INC
Stock option (right to buy) 		M - Exercise X -49,374 16,193 -75.30
2018-05-29 2018-05-23 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -299 0 -100.00 92.03 -27,517
2018-05-29 2018-05-23 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -9,301 299 -96.89 91.60 -851,972 27,388
2018-05-29 2018-05-23 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -39,774 9,600 -80.56 90.11 -3,584,035 865,056
2018-05-29 2018-05-23 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		M - Exercise X 49,374 49,374 0.30 14,936 14,936
2018-05-03 2018-05-01 4 AGIO AGIOS PHARMACEUTICALS INC
Stock option (right to buy) 		M - Exercise X -13,000 65,567 -16.55
2018-05-03 2018-05-01 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -100 0 -100.00 84.35 -8,435
2018-05-03 2018-05-01 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -2,814 100 -96.57 83.56 -235,138 8,356
2018-05-03 2018-05-01 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -10,086 2,914 -77.58 82.88 -835,928 241,512
2018-05-03 2018-05-01 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		M - Exercise X 13,000 13,000 0.30 3,932 3,932
2018-04-04 2018-04-02 4 AGIO AGIOS PHARMACEUTICALS INC
Stock option (right to buy) 		M - Exercise X -13,000 78,567 -14.20
2018-04-04 2018-04-02 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -2,113 0 -100.00 79.49 -167,962
2018-04-04 2018-04-02 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -3,390 2,113 -61.60 78.59 -266,420 166,061
2018-04-04 2018-04-02 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -3,340 5,503 -37.77 77.76 -259,718 427,913
2018-04-04 2018-04-02 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -2,600 8,843 -22.72 76.40 -198,640 675,605
2018-04-04 2018-04-02 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -1,557 11,443 -11.98 75.54 -117,616 864,404
2018-04-04 2018-04-02 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		M - Exercise X 13,000 13,000 0.30 3,932 3,932
2018-03-05 2018-03-01 4 AGIO AGIOS PHARMACEUTICALS INC
Stock option (right to buy) 		M - Exercise X -13,000 91,567 -12.43
2018-03-05 2018-03-01 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -10,085 0 -100.00 81.30 -819,910
2018-03-05 2018-03-01 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -2,915 10,085 -22.42 80.38 -234,308 810,632
2018-03-05 2018-03-01 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		M - Exercise X 13,000 13,000 0.30 3,932 3,932
2018-02-20 2018-02-16 4 AGIO AGIOS PHARMACEUTICALS INC
Restricted stock units 		A - Award 24,375 24,375
2018-02-20 2018-02-16 4 AGIO AGIOS PHARMACEUTICALS INC
Stock option (right to buy) 		A - Award 97,500 97,500
2018-02-05 2018-02-01 4 AGIO AGIOS PHARMACEUTICALS INC
Stock option (right to buy) 		M - Exercise X -13,000 104,567 -11.06
2018-02-05 2018-02-01 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -4,460 0 -100.00 79.23 -353,366
2018-02-05 2018-02-01 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -8,540 4,460 -65.69 78.50 -670,390 350,110
2018-02-05 2018-02-01 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		M - Exercise X 13,000 13,000 0.30 3,932 3,932
2018-01-30 2018-01-26 4 AGIO AGIOS PHARMACEUTICALS INC
Stock option (right to buy) 		M - Exercise X -23,572 117,567 -16.70
2018-01-30 2018-01-26 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -2,966 0 -100.00 82.22 -243,865
2018-01-30 2018-01-26 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -11,369 2,966 -79.31 81.40 -925,437 241,432
2018-01-30 2018-01-26 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -9,237 14,335 -39.19 80.35 -742,193 1,151,817
2018-01-30 2018-01-26 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		M - Exercise X 23,572 23,572 0.30 7,131 7,131
2018-01-26 2018-01-24 4 AGIO AGIOS PHARMACEUTICALS INC
Stock option (right to buy) 		M - Exercise X -20 141,139 -0.01
2018-01-26 2018-01-24 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -20 0 -100.00 80.01 -1,600
2018-01-26 2018-01-24 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		M - Exercise X 20 20 0.30 6 6
2018-01-25 2018-01-24 4 AGIO AGIOS PHARMACEUTICALS INC
Stock option (right to buy) 		M - Exercise X -13,533 141,159 -8.75
2018-01-25 2018-01-24 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -13,533 0 -100.00 80.01 -1,082,775
2018-01-25 2018-01-24 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		M - Exercise X 13,533 13,533 0.30 4,094 4,094
2018-01-25 2018-01-23 4 AGIO AGIOS PHARMACEUTICALS INC
Stock option (right to buy) 		M - Exercise X -32,875 5,962 -84.65
2018-01-25 2018-01-23 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -32,875 0 -100.00 80.01 -2,630,329
2018-01-25 2018-01-23 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		M - Exercise X 32,875 32,875 0.30 9,945 9,945
2018-01-25 2017-12-01 4/A AGIO AGIOS PHARMACEUTICALS INC
Stock option (right to buy) 		M - Exercise X -6,000 38,837 -13.38
2018-01-16 2018-01-16 4 AGIO AGIOS PHARMACEUTICALS INC
Stock option (right to buy) 		M - Exercise X -53,000 154,692 -25.52
2018-01-16 2018-01-16 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -6,597 0 -100.00 74.80 -493,456
2018-01-16 2018-01-16 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -10,914 6,597 -62.33 74.11 -808,837 488,904
2018-01-16 2018-01-16 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -22,304 17,511 -56.02 73.02 -1,628,638 1,278,653
2018-01-16 2018-01-16 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -13,185 39,815 -24.88 71.77 -946,287 2,857,523
2018-01-16 2018-01-16 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		M - Exercise X 53,000 53,000 0.30 16,032 16,032
2017-12-12 2017-12-12 4 DNLI Denali Therapeutics Inc.
Series A-1 Preferred Stock 		C - Conversion -19,774 0 -100.00
2017-12-12 2017-12-12 4 DNLI Denali Therapeutics Inc.
Series A-1 Preferred Stock 		C - Conversion -19,774 0 -100.00
2017-12-12 2017-12-12 4 DNLI Denali Therapeutics Inc.
Series A-1 Preferred Stock 		C - Conversion -105,225 0 -100.00
2017-12-12 2017-12-12 4 DNLI Denali Therapeutics Inc.
Series A-1 Preferred Stock 		C - Conversion -105,225 0 -100.00
2017-12-12 2017-12-12 4 DNLI Denali Therapeutics Inc.
Common Stock 		C - Conversion 19,774 19,774
2017-12-12 2017-12-12 4 DNLI Denali Therapeutics Inc.
Common Stock 		C - Conversion 19,774 19,774
2017-12-12 2017-12-12 4 DNLI Denali Therapeutics Inc.
Common Stock 		C - Conversion 105,225 105,225
2017-12-12 2017-12-12 4 DNLI Denali Therapeutics Inc.
Common Stock 		C - Conversion 105,225 105,225
2017-12-08 2017-12-07 4 DNLI Denali Therapeutics Inc.
Stock Option (right to buy) 		A - Award 47,165 47,165
2017-12-07 3 DNLI Denali Therapeutics Inc.
Common Stock 		150,000
2017-12-07 3 DNLI Denali Therapeutics Inc.
Common Stock 		150,000
2017-12-05 2017-12-01 4 AGIO AGIOS PHARMACEUTICALS INC
Stock option (right to buy) 		M - Exercise X -6,000 20,656 -22.51
2017-12-05 2017-12-01 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -400 0 -100.00 62.08 -24,832
2017-12-05 2017-12-01 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -5,600 400 -93.33 61.51 -344,456 24,604
2017-12-05 2017-12-01 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		M - Exercise X 6,000 6,000 0.30 1,815 1,815
2017-11-03 2017-11-01 4 AGIO AGIOS PHARMACEUTICALS INC
Stock option (right to buy) 		M - Exercise X -6,000 26,656 -18.37
2017-11-03 2017-11-01 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -4,260 0 -100.00 63.32 -269,743
2017-11-03 2017-11-01 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -942 4,260 -18.11 64.64 -60,891 275,366
2017-11-03 2017-11-01 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -598 5,202 -10.31 65.42 -39,121 340,315
2017-11-03 2017-11-01 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -200 5,800 -3.33 66.75 -13,350 387,150
2017-11-03 2017-11-01 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		M - Exercise X 6,000 6,000 0.30 1,815 1,815
2017-10-05 2017-10-04 4 AGIO AGIOS PHARMACEUTICALS INC
Stock option (right to buy) 		M - Exercise X -80,000 32,656 -71.01
2017-10-05 2017-10-04 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -80,000 0 -100.00 70.14 -5,611,200
2017-10-05 2017-10-04 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		M - Exercise X 80,000 80,000 0.30 24,200 24,200
2017-10-04 2017-10-02 4 AGIO AGIOS PHARMACEUTICALS INC
Stock option (right to buy) 		M - Exercise X -6,000 112,656 -5.06
2017-10-04 2017-10-02 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -6,000 0 -100.00 66.76 -400,560
2017-10-04 2017-10-02 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		M - Exercise X 6,000 6,000 0.30 1,815 1,815
2017-09-20 2017-09-18 4 AGIO AGIOS PHARMACEUTICALS INC
Stock option (right to buy) 		M - Exercise X -35,000 118,656 -22.78
2017-09-20 2017-09-18 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -35,000 0 -100.00 67.12 -2,349,200
2017-09-20 2017-09-18 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		M - Exercise X 35,000 35,000 0.30 10,588 10,588
2017-09-20 2017-09-07 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		G - Gift -500 271,772 -0.18
2017-09-05 2017-08-31 4 BLUE bluebird bio, Inc.
Stock Option (right to buy) 		M - Exercise -2,000 19,361 -9.36
2017-09-05 2017-08-31 4 BLUE bluebird bio, Inc.
Common Stock 		S - Sale -2,000 3,176 -38.64 115.07 -230,145 365,470
2017-09-05 2017-08-31 4 BLUE bluebird bio, Inc.
Common Stock 		M - Exercise 2,000 5,176 62.97 8.16 16,312 42,214
2017-09-05 2017-09-01 4 AGIO AGIOS PHARMACEUTICALS INC
Stock option (right to buy) 		M - Exercise X -6,000 153,656 -3.76
2017-09-05 2017-09-01 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -6,000 0 -100.00 62.20 -373,200
2017-09-05 2017-09-01 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		M - Exercise X 6,000 6,000 0.30 1,815 1,815
2017-08-03 2017-08-02 4 AGIO AGIOS PHARMACEUTICALS INC
Stock option (right to buy) 		M - Exercise X -24,000 159,656 -13.07
2017-08-03 2017-08-02 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -24,000 0 -100.00 60.55 -1,453,200
2017-08-03 2017-08-02 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		M - Exercise X 24,000 24,000 0.30 7,260 7,260
2017-08-03 2017-08-01 4 AGIO AGIOS PHARMACEUTICALS INC
Stock option (right to buy) 		M - Exercise X -3,000 183,656 -1.61
2017-08-03 2017-08-01 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -3,000 0 -100.00 55.12 -165,360
2017-08-03 2017-08-01 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		M - Exercise X 3,000 3,000 0.30 908 908
2017-07-06 2017-07-03 4 AGIO AGIOS PHARMACEUTICALS INC
Stock option (right to buy) 		M - Exercise X -3,000 186,656 -1.58
2017-07-06 2017-07-03 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -3,000 0 -100.00 51.18 -153,540
2017-07-06 2017-07-03 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		M - Exercise X 3,000 3,000 0.30 908 908
2017-06-12 2017-06-08 4 BLUE bluebird bio, Inc.
Stock Option (right to buy) 		A - Award 4,000 4,000
2017-06-12 2017-06-08 4 BLUE bluebird bio, Inc.
Common Stock 		A - Award 1,000 3,176 45.96
2017-06-08 2017-06-07 4 AGIO AGIOS PHARMACEUTICALS INC
Stock option (right to buy) 		M - Exercise X -1,900 189,656 -0.99
2017-06-08 2017-06-07 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -1,900 0 -100.00 50.02 -95,038
2017-06-08 2017-06-07 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		M - Exercise X 1,900 1,900 0.30 575 575
2017-06-08 2017-06-06 4 AGIO AGIOS PHARMACEUTICALS INC
Stock option (right to buy) 		M - Exercise X -1,100 191,556 -0.57
2017-06-08 2017-06-06 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -1,100 0 -100.00 50.02 -55,022
2017-06-08 2017-06-06 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		M - Exercise X 1,100 1,100 0.30 333 333
2017-05-02 2017-05-01 4 AGIO AGIOS PHARMACEUTICALS INC
Stock option (right to buy) 		M - Exercise X -3,000 192,656 -1.53
2017-05-02 2017-05-01 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -3,000 0 -100.00 50.06 -150,180
2017-05-02 2017-05-01 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		M - Exercise X 3,000 3,000 0.30 908 908
2017-04-05 2017-04-03 4 AGIO AGIOS PHARMACEUTICALS INC
Stock option (right to buy) 		M - Exercise X -3,000 195,656 -1.51
2017-04-05 2017-04-03 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -3,000 0 -100.00 58.62 -175,860
2017-04-05 2017-04-03 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		M - Exercise X 3,000 3,000 0.30 908 908
2017-03-03 2017-03-01 4 BLUE bluebird bio, Inc.
Stock Option (right to buy) 		M - Exercise -5,000 21,361 -18.97
2017-03-03 2017-03-01 4 BLUE bluebird bio, Inc.
Common Stock 		S - Sale -5,000 2,176 -69.68 89.53 -447,632 194,810
2017-03-03 2017-03-01 4 BLUE bluebird bio, Inc.
Common Stock 		M - Exercise 5,000 7,176 229.78 8.16 40,779 58,526
2017-03-03 2017-03-01 4 AGIO AGIOS PHARMACEUTICALS INC
Stock option (right to buy) 		M - Exercise X -3,000 198,656 -1.49
2017-03-03 2017-03-01 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -3,000 0 -100.00 50.47 -151,410
2017-03-03 2017-03-01 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		M - Exercise X 3,000 3,000 0.30 908 908
2017-02-23 2017-02-21 4 AGIO AGIOS PHARMACEUTICALS INC
Stock option (right to buy) 		A - Award 142,900 142,900
2017-02-17 2017-02-16 4 AGIO AGIOS PHARMACEUTICALS INC
Stock option (right to buy) 		M - Exercise X -6,000 201,656 -2.89
2017-02-17 2017-02-16 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -6,000 0 -100.00 50.01 -300,060
2017-02-17 2017-02-16 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		M - Exercise X 6,000 6,000 0.30 1,815 1,815
2017-01-27 2017-01-26 4 AGIO AGIOS PHARMACEUTICALS INC
Stock option (right to buy) 		A - Award 68,182 136,363 100.00
2017-01-23 2016-06-02 4/A BLUE bluebird bio, Inc.
Common Stock 		A - Award 1,000 2,176 85.03
2016-06-20 2016-06-16 4 FMI Foundation Medicine, Inc.
Common Stock 		A - Award 12,075 23,326 107.32 19.93 240,655 464,887
2016-06-03 2016-06-02 4 BLUE bluebird bio, Inc.
Stock Option (right to buy) 		A - Award 4,000 4,000
2016-06-03 2016-06-02 4 BLUE bluebird bio, Inc.
Common Stock 		A - Award 1,000 1,000
2016-02-18 2016-02-16 4 AGIO AGIOS PHARMACEUTICALS INC
Stock option (right to buy) 		A - Award 102,000 997,501 11.39
2016-01-11 2016-01-07 4 AGIO AGIOS PHARMACEUTICALS INC
Stock option (right to buy) 		M - Exercise -20,000 895,501 -2.18
2016-01-11 2016-01-07 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		M - Exercise 20,000 272,272 7.93 0.30 6,050 82,362
2016-01-05 2016-01-05 4 AGIO AGIOS PHARMACEUTICALS INC
Stock option (right to buy) 		M - Exercise -10,000 915,501 -1.08
2016-01-05 2016-01-05 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		M - Exercise 10,000 252,272 4.13 0.30 3,025 76,312
2016-01-05 2016-01-04 4 AGIO AGIOS PHARMACEUTICALS INC
Stock option (right to buy) 		M - Exercise -10,000 925,501 -1.07
2016-01-05 2016-01-04 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		M - Exercise 10,000 242,272 4.31 0.30 3,025 73,287
2015-12-07 2015-12-03 4 AGIO AGIOS PHARMACEUTICALS INC
Stock option (right to buy) 		A - Award 68,181 935,501 7.86
2015-10-30 2015-10-27 4 AGIO AGIOS PHARMACEUTICALS INC
Stock option (right to buy) 		M - Exercise X -4,000 867,320 -0.46
2015-10-30 2015-10-27 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -4,000 232,272 -1.69 80.26 -321,040 18,642,151
2015-10-30 2015-10-27 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		M - Exercise X 4,000 236,272 1.72 31.64 126,560 7,475,646
2015-08-05 2015-08-03 4 AGIO AGIOS PHARMACEUTICALS INC
Stock option (right to buy) 		M - Exercise X -7,299 871,320 -0.83
2015-08-05 2015-08-03 4 AGIO AGIOS PHARMACEUTICALS INC
Stock option (right to buy) 		M - Exercise X -701 878,619 -0.08
2015-08-05 2015-08-03 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -8,000 232,272 -3.33 110.60 -884,800 25,689,283
2015-08-05 2015-08-03 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		M - Exercise X 7,299 240,272 3.13 31.64 230,940 7,602,206
2015-08-05 2015-08-03 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		M - Exercise X 701 232,973 0.30 0.30 212 70,474
2015-06-22 2015-06-18 4 FMI Foundation Medicine, Inc.
Common Stock 		A - Award 5,997 11,251 114.14 32.23 193,283 362,620
2015-06-08 2015-06-04 4 BLUE bluebird bio, Inc.
Stock Option (right to buy) 		A - Award 7,500 7,500
2015-06-02 2015-06-01 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -6,500 232,272 -2.72 120.67 -784,355 28,028,262
2015-06-02 2015-06-01 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -6,500 232,272 -2.72 120.67 -784,355 28,028,262
2015-05-28 2015-05-27 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -8,929 85,582 -9.45 120.05 -1,071,926 10,274,119
2015-05-28 2015-03-12 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		G - Gift -190 94,511 -0.20
2015-05-13 2015-05-12 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -2,093 94,701 -2.16 110.03 -230,293 10,419,951
2015-05-13 2015-05-11 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -3,107 96,794 -3.11 110.01 -341,801 10,648,308
2015-05-11 2015-05-08 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -1,300 99,901 -1.28 101.32 -131,716 10,121,969
2015-05-11 2015-05-08 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -2,600 238,772 -1.08 101.32 -263,432 24,192,379
2015-05-11 2015-05-07 4 AGIO AGIOS PHARMACEUTICALS INC
Stock option (right to buy) 		M - Exercise -10,000 879,320 -1.12
2015-05-11 2015-05-07 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		M - Exercise 10,000 241,372 4.32 0.30 3,025 73,015
2015-05-05 2015-05-01 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -3,900 231,372 -1.66 93.63 -365,157 21,663,360
2015-04-15 2015-04-13 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -1,300 101,201 -1.27 100.03 -130,039 10,123,136
2015-04-15 2015-04-13 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -2,600 235,272 -1.09 100.03 -260,078 23,534,258
2015-04-14 2015-04-07 4/A FMI Foundation Medicine, Inc.
Common Stock 		U - Other -25,996 5,254 -83.19 50.00 -1,299,800 262,700
2015-04-14 2015-04-07 4/A FMI Foundation Medicine, Inc.
Common Stock 		U - Other -25,996 5,254 -83.19 50.00 -1,299,800 262,700
2015-04-14 2015-04-07 4/A FMI Foundation Medicine, Inc.
Common Stock 		U - Other -25,996 5,254 -83.19 50.00 -1,299,800 262,700
2015-04-09 2015-04-07 4 FMI Foundation Medicine, Inc.
Common Stock 		U - Other -25,218 6,032 -80.70 50.00 -1,260,900 301,600
2015-04-09 2015-04-07 4 FMI Foundation Medicine, Inc.
Common Stock 		U - Other -25,218 6,032 -80.70 50.00 -1,260,900 301,600
2015-04-09 2015-04-07 4 FMI Foundation Medicine, Inc.
Common Stock 		U - Other -25,218 6,032 -80.70 50.00 -1,260,900 301,600
2015-04-03 2015-04-01 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -3,900 237,872 -1.61 92.54 -360,906 22,012,675
2015-03-09 2015-03-05 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -2,600 102,501 -2.47 110.16 -286,416 11,291,510
2015-03-03 2015-03-02 4 AGIO AGIOS PHARMACEUTICALS INC
Stock option (right to buy) 		A - Award 136,000 889,320 18.05
2015-03-03 2015-03-02 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -1,300 105,101 -1.22 107.05 -139,165 11,251,062
2015-03-03 2015-03-02 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -6,500 241,772 -2.62 107.05 -695,825 25,881,693
2015-03-03 2015-02-27 4 AGIO AGIOS PHARMACEUTICALS INC
Stock option (right to buy) 		M - Exercise -25,000 753,320 -3.21
2015-03-03 2015-02-27 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		M - Exercise 25,000 248,272 11.20 0.30 7,562 75,102
2015-02-13 2015-02-13 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -684 106,401 -0.64 120.31 -82,292 12,801,104
2015-02-13 2015-02-11 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -787 107,085 -0.73 120.14 -94,550 12,865,192
2015-02-03 2015-02-02 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -3,900 107,872 -3.49 114.31 -445,809 12,330,848
2015-02-03 2015-02-02 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -6,500 223,272 -2.83 114.31 -743,015 25,522,222
2015-01-06 2015-01-02 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -6,500 111,772 -5.50 110.08 -715,520 12,303,862
2015-01-06 2015-01-02 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -6,500 229,772 -2.75 110.08 -715,520 25,293,302
2014-12-22 2014-12-19 4 BLUE bluebird bio, Inc.
Common Stock 		P - Purchase 1,176 1,176 85.00 99,960 99,960
2014-12-02 2014-12-01 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -6,500 118,272 -5.21 97.03 -630,695 11,475,932
2014-12-02 2014-12-01 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -6,500 118,272 -5.21 97.03 -630,695 11,475,932
2014-11-04 2014-11-03 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -6,500 124,772 -4.95 81.71 -531,115 10,195,120
2014-11-04 2014-11-03 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -6,500 124,772 -4.95 81.71 -531,115 10,195,120
2014-10-03 2014-10-01 4 AGIO AGIOS PHARMACEUTICALS INC
Stock option (right to buy) 		M - Exercise X -2,500 778,320 -0.32
2014-10-03 2014-10-01 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -6,500 131,272 -4.72 60.07 -390,455 7,885,509
2014-10-03 2014-10-01 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -6,500 131,272 -4.72 60.07 -390,455 7,885,509
2014-10-03 2014-10-01 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		M - Exercise X 2,500 255,772 0.99 0.30 756 77,371
2014-09-29 2014-09-26 4 AGIO AGIOS PHARMACEUTICALS INC
Stock option (right to buy) 		M - Exercise X -30,000 780,820 -3.70
2014-09-29 2014-09-26 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -30,000 137,772 -17.88 62.68 -1,880,400 8,635,549
2014-09-29 2014-09-26 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -30,000 137,772 -17.88 62.68 -1,880,400 8,635,549
2014-09-29 2014-09-26 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		M - Exercise X 30,000 283,272 11.84 0.30 9,075 85,690
2014-09-03 2014-09-02 4 AGIO AGIOS PHARMACEUTICALS INC
Stock option (right to buy) 		M - Exercise -6,500 810,820 -0.80
2014-09-03 2014-09-02 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -6,500 167,772 -3.73 46.30 -300,950 7,767,844
2014-09-03 2014-09-02 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -6,500 167,772 -3.73 46.30 -300,950 7,767,844
2014-09-03 2014-09-02 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		M - Exercise X 6,500 259,772 2.57 0.30 1,966 78,581
2014-08-12 2014-08-11 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -2,265 174,272 -1.28 40.17 -90,985 7,000,506
2014-08-12 2014-08-11 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -2,265 253,272 -0.89 40.17 -90,985 10,173,936
2014-08-05 2014-08-01 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -4,235 176,537 -2.34 39.17 -165,885 6,914,954
2014-08-05 2014-08-01 4 AGIO AGIOS PHARMACEUTICALS INC
Common stock 		S - Sale X -4,235 255,537 -1.63 39.17 -165,885 10,009,384
2014-07-02 2014-07-01 4 AGIO AGIOS PHARMACEUTICALS INC
Common Stock 		S - Sale X -6,500 180,772 -3.47 46.52 -302,380 8,409,513
2014-07-02 2014-07-01 4 AGIO AGIOS PHARMACEUTICALS INC
Common Stock 		S - Sale X -6,500 259,772 -2.44 46.52 -302,380 12,084,593
2014-06-20 2014-06-18 4 FMI Foundation Medicine, Inc.
Stock Option (right to buy) 		A - Award 13,385 13,385
2014-06-12 2014-06-11 4 BLUE bluebird bio, Inc.
Stock Option (right to buy) 		A - Award 7,500 7,500
2014-04-08 2014-04-04 4 AGIO AGIOS PHARMACEUTICALS INC
Stock option (right to buy) 		A - Award 54,546 817,320 7.15
2014-03-27 2014-03-25 4 AGIO AGIOS PHARMACEUTICALS INC
Stock Option (Right to Buy) 		M - Exercise -25,000 762,774 -3.17
2014-03-27 2014-03-25 4 AGIO AGIOS PHARMACEUTICALS INC
Common Stock 		M - Exercise 25,000 266,272 10.36 0.30 7,562 80,547
2014-03-12 2014-03-10 4 AGIO AGIOS PHARMACEUTICALS INC
Stock Option (Right to Buy) 		M - Exercise -54,000 787,774 -6.42
2014-03-12 2014-03-10 4 AGIO AGIOS PHARMACEUTICALS INC
Common Stock 		M - Exercise 54,000 241,272 28.84 0.30 16,335 72,985
2014-03-07 2014-03-05 4 AGIO AGIOS PHARMACEUTICALS INC
Stock Option (Right to Buy) 		A - Award 160,000 841,774 23.47
2013-10-02 2013-09-30 4 FMI Foundation Medicine, Inc.
Series A Convertible Preferred Stock 		C - Conversion -125,000 0 -100.00
2013-10-02 2013-09-30 4 FMI Foundation Medicine, Inc.
Series A Convertible Preferred Stock 		C - Conversion -125,000 0 -100.00
2013-10-02 2013-09-30 4 FMI Foundation Medicine, Inc.
Common Stock 		C - Conversion 31,250 31,250
2013-10-02 2013-09-30 4 FMI Foundation Medicine, Inc.
Common Stock 		C - Conversion 31,250 31,250
2013-09-24 3 FMI Foundation Medicine, Inc.
Common Stock 		31,250
2013-07-23 3 AGIO AGIOS PHARMACEUTICALS INC
Common Stock 		187,272
2013-07-23 3 AGIO AGIOS PHARMACEUTICALS INC
Common Stock 		187,272
P
गैर-डेरिवेटिव या डेरिवेटिव प्रतिभूति की खुला बाज़ार या निजी खरीद
S
गैर-डेरिवेटिव या डेरिवेटिव प्रतिभूति का खुला बाज़ार या निजी बिक्री
A
कंपनी से प्रतिभूतियों का अनुदान, पुरस्कार या अन्य अधिग्रहण (जैसे एक ऑप्शन)
C
डेरिवेटिव का रूपांतरण
D
कंपनी को प्रतिभूतियों की बिक्री या हस्तांतरण
F
कंपनी से प्राप्त प्रतिभूतियों के हिस्से का उपयोग करके एक्सरसाइज मूल्य या कर दायित्व का भुगतान
G
इनसाइडर द्वारा या उसे प्रतिभूतियों का उपहार
K
इक्विटी स्वैप और समान हेजिंग लेनदेन
M
कंपनी से प्राप्त डेरिवेटिव प्रतिभूति के एक्सरसाइज या रूपांतरण (जैसे कि एक ऑप्शन)
V
किसी लेन-देन को स्वेच्छा से फॉर्म 4 पर रिपोर्ट किया गया
J
अन्य (लेन-देन का वर्णन करने वाले फ़ुटनोट के साथ)