UTHR / United Therapeutics Corporation - SEC फाइलिंग, वार्षिक रिपोर्ट, प्रॉक्सी स्टेटमेंट

यूनाइटेड थेरेप्यूटिक्स कॉर्पोरेशन
US ˙ NasdaqGS ˙ US91307C1027

मूलभूत आँकड़े
LEI 5299005C4HZL4UWROC14
CIK 1082554
SEC Filings
All companies that sell securities in the United States must register with the Securities and Exchange Commission (SEC) and file reports on a regular basis. These reports include company annual reports (10K, 10Q), news updates (8K), investor presentations (found in 8Ks), insider trades (form 4), ownership reports (13D, and 13G), and reports related to the specific securities sold, such as registration statements and prospectus. This page shows recent SEC filings related to United Therapeutics Corporation
SEC Filings (Chronological Order)
यह पृष्ठ SEC फाइलिंग की एक पूरी, कालानुक्रमिक सूची प्रदान करता है, ओनरशिप फाइलिंग को छोड़कर, जो हम अन्यत्र प्रदान करते हैं।
September 2, 2025 EX-99.1

For Immediate Release

Exhibit 99.1 For Immediate Release United Therapeutics Corporation Announces TETON-2 Pivotal Study of Tyvaso® Meets Primary Endpoint for the Treatment of Idiopathic Pulmonary Fibrosis Positive results were observed across all subgroups Study meets several key secondary endpoints with statistical significance SILVER SPRING, Md. and RESEARCH TRIANGLE PARK, N.C., September 2, 2025: United Therapeutic

September 2, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 2, 2025 United Therape

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 2, 2025 United Therapeutics Corporation (Exact Name of Registrant as Specified in its Charter) Delaware 000-26301 52-1984749 (State or Other (Commission (I.R.S. Employer Ju

August 1, 2025 EX-99.1

For Immediate Release

Exhibit 99.1 For Immediate Release United Therapeutics Corporation Announces $1 Billion Accelerated Share Repurchase Program Repurchase reflects the strength of United Therapeutics’ balance sheet and confidence in its near-term prospects SILVER SPRING, Md. and RESEARCH TRIANGLE PARK, N.C., August 1, 2025: United Therapeutics Corporation (Nasdaq: UTHR), a public benefit corporation, announced that

August 1, 2025 EX-10.1

Re: Collared Accelerated Share Repurchase

Exhibit 10.1 Execution Version United Therapeutics Corporation 1000 Spring Street Silver Spring MD 20910 Attention: James Edgemond, Chief Financial Officer and Treasurer Re: Collared Accelerated Share Repurchase Ladies and Gentlemen: This master confirmation (this “Master Confirmation”), dated as of August 1, 2025 is intended to set forth certain terms and provisions of certain Transactions (each,

August 1, 2025 8-K

Regulation FD Disclosure, Entry into a Material Definitive Agreement, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 1, 2025 United Therapeutics Corporation (Exact Name of Registrant as Specified in its Charter) Delaware 000-26301 52-1984749 (State or Other (Commission (I.R.S. Employer Juris

July 30, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 30, 2025 United Therapeutic

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 30, 2025 United Therapeutics Corporation (Exact Name of Registrant as Specified in Charter) Delaware 000-26301 52-1984749 (State or Other Jurisdiction of Incorporation) (Commiss

July 30, 2025 EX-99.1

Three Months Ended June 30, Dollar Change Percentage Change 2025 2024 Total revenues $ 798.6 $ 714.9 $ 83.7 12 % Net income $ 309.5 $ 278.1 $ 31.4 11 % Net income, per basic share $ 6.86 $ 6.26 $ 0.60 10 % Net income, per diluted share $ 6.41 $ 5.85

Exhibit 99.1 For Immediate Release United Therapeutics Corporation Reports Record Second Quarter 2025 Financial Results Record total revenue of $799 million, reflecting 12 percent growth over the second quarter of 2024 and 12 consecutive quarters of double-digit, year-over-year total revenue growth Share repurchase of up to $1 billion authorized by the Board of Directors, expiring March 31, 2026 T

July 30, 2025 EX-10.3

Eighth Amendment to Specialty Pharmacy Network Agreement, dated as of April 11, 2025, between the Registrant and Accredo Health Group, Inc.

Exhibit 10.3 EIGHTH AMENDMENT TO SPECIALTY PHARMACY NETWORK AGREEMENT This Eighth Amendment to Specialty Pharmacy Network Agreement (this “Amendment”) is made as of the date the last Party executes this Amendment (the “Amendment Effective Date”), by and between Accredo Health Group, Inc. (“Specialty Pharmacy”), and United Therapeutics Corporation (“UT”). Specialty Pharmacy and UT are each referred

July 30, 2025 EX-FILING FEES

Filing Fee Table*

Exhibit 107.1 CALCULATION OF FILING FEE TABLES Form S-8 (Form Type) United Therapeutics Corporation (Exact Name of Registrant as Specified in its Charter) TABLE 1 – NEWLY REGISTERED SECURITIES Security Type Security Class Title Fee Calculation Rule Amount Registered(1) Proposed Maximum Offering Price Per Unit Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee Equity Common Stock,

July 30, 2025 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934. For the quarterly period ended June 30, 2025 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934. For the transition period from to Commission file number 0

July 30, 2025 S-8

As filed with the Securities and Exchange Commission on July 30, 2025

As filed with the Securities and Exchange Commission on July 30, 2025 Registration No.

June 27, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 26, 2025 United Therapeutic

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 26, 2025 United Therapeutics Corporation (Exact Name of Registrant as Specified in its Charter) Delaware 000-26301 52-1984749 (State or Other (Commission (I.R.S. Employer Jurisd

June 27, 2025 EX-10.1

United Therapeutics Corporation Amended and Restated 2015 Stock Incentive Plan

Exhibit 10.1 UNITED THERAPEUTICS CORPORATION AMENDED AND RESTATED 2015 STOCK INCENTIVE PLAN (effective June 26, 2025) 1. Purpose The purpose of the United Therapeutics Corporation Amended and Restated 2015 Stock Incentive Plan (this “Plan”) is to advance the interests of United Therapeutics Corporation (the “Company”) by stimulating the efforts of employees, officers, non-employee directors and ot

May 30, 2025 SD

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM SD SPECIALIZED DISCLOSURE REPORT United Therapeutics Corporation (Exact Name of Registrant as Specified in Charter)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM SD SPECIALIZED DISCLOSURE REPORT United Therapeutics Corporation (Exact Name of Registrant as Specified in Charter) Delaware 000-26301 52-1984749 (State or Other (Commission (I.R.S. Employer Jurisdiction of File Number) Identification Number) Incorporation or Organization) 1000 Spring Street Silver Spring, MD 20910 (Addre

April 30, 2025 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934. For the quarterly period ended March 31, 2025 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934. For the transition period from to Commission file number

April 30, 2025 EX-99.1

Three Months Ended March 31, Dollar Change Percentage Change 2025 2024 Total revenues $ 794.4 $ 677.7 $ 116.7 17 % Net income $ 322.2 $ 306.6 $ 15.6 5 % Net income, per basic share $ 7.18 $ 6.52 $ 0.66 10 % Net income, per diluted share $ 6.63 $ 6.17

Exhibit 99.1 For Immediate Release United Therapeutics Corporation Reports First Quarter 2025 Financial Results SILVER SPRING, Md. and RESEARCH TRIANGLE PARK, N.C., April 30, 2025: United Therapeutics Corporation (Nasdaq: UTHR), a public benefit corporation, today announced its financial results for the quarter ended March 31, 2025. Total revenues in the first quarter of 2025 grew 17 percent year-

April 30, 2025 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 30, 2025 United Therapeutics Corporation (Exact Name of Registrant as Specified in Charter) Delaware 000-26301 52-1984749 (State or Other Jurisdiction of Incorporation) (Commis

April 29, 2025 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant x Filed by a Party other than the Registran

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant x Filed by a Party other than the Registrant o Check the appropriate box: o Preliminary Proxy Statement o Confidential, for Use of the Commission Only (as permitted by Rule 14a‑6(e)(2)) o Defin

April 29, 2025 DEF 14A

DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant x Filed by a Party other than the Registrant o Check the appropriate box: o Preliminary Proxy Statement o Confidential, for Use of the Commission Only (as permitted by Rule 14a‑6(e)(2)) x Defin

April 28, 2025 EX-10.1

Credit Agreement, dated as of April 25, 2025, among the Registration, the lenders referred to therein, and Wells Fargo Bank, National Association, as administrative agent and as a swingline lender, incorporated by reference to Exhibit 10.1 to the Registrant’s Current Report on Form 8-K filed on April 28, 2025

Exhibit 10.1 Execution Version $2,500,000,000 CREDIT AGREEMENT dated as of April 25, 2025 by and among UNITED THERAPEUTICS CORPORATION, as Borrower, CERTAIN SUBSIDIARIES OF THE BORROWER PARTY HERETO, as Guarantors, THE LENDERS REFERRED TO HEREIN, as Lenders, BANK OF AMERICA, N.A., DNB MARKETS, INC., JPMORGAN CHASE BANK, N.A., PNC BANK, NATIONAL ASSOCIATION and U.S. BANK NATIONAL ASSOCIATION, as co

April 28, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 25, 2025 United Therapeuti

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 25, 2025 United Therapeutics Corporation (Exact Name of Registrant as Specified in its Charter) Delaware 000-26301 52-1984749 (State or Other (Commission (I.R.S. Employer Juris

February 26, 2025 EX-10.28

Employee Directors in 2025 and thereafter under the United Therapeutics Corporation 2015 Stock Incentive Plan.

Exhibit 10.28 UNITED THERAPEUTICS CORPORATION GRANT NOTICE FOR 2015 STOCK INCENTIVE PLAN NONQUALIFIED STOCK OPTIONS FOR NON-EMPLOYEE DIRECTORS FOR GOOD AND VALUABLE CONSIDERATION, United Therapeutics Corporation (the “Company”), hereby grants to Participant named below the nonqualified stock option (the “Option”) to purchase any part or all of the number of shares of its par value common stock (th

February 26, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 26, 2025 United Therape

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 26, 2025 United Therapeutics Corporation (Exact Name of Registrant as Specified in Charter) Delaware 000-26301 52-1984749 (State or Other Jurisdiction of Incorporation) (Com

February 26, 2025 EX-19

nsider Trading Policy

Exhibit 19 UNITED THERAPEUTICS CORPORATION AND SUBSIDIARIES STATEMENT OF COMPANY POLICY Securities Trades by Company Personnel United Therapeutics Corporation (the “Company”) has adopted this policy on insider trading (this “Policy”), which applies to each officer, director and employee of the Company or any of its subsidiaries, in order to reduce the risk of securities laws violations that could have severe civil and criminal consequences.

February 26, 2025 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K (Mark One) ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934. For the fiscal year ended December 31, 2024 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934. For the transition period from to Commission file number 0-26301 United Therapeu

February 26, 2025 EX-21

Subsidiaries of the Registrant.

Exhibit 21 SUBSIDIARIES OF THE REGISTRANT IVIVA Medical, Inc., a Delaware corporation Lung Bioengineering Inc., a Delaware corporation Miromatrix Medical Inc., a Delaware corporation Revivicor, Inc., a Delaware corporation United Therapeutics Europe, Ltd., a company incorporated under the laws of England and Wales United Therapeutics Ireland Limited, a company incorporated under the laws of Irelan

February 26, 2025 EX-99.1

Three Months Ended December 31, Year Ended December 31, 2024 2023 2024 2023 Total revenues $ 735.9 $ 614.7 $ 2,877.4 $ 2,327.5 Net income $ 301.3 $ 217.1 $ 1,195.1 $ 984.8 Net income, per basic share $ 6.74 $ 4.62 $ 26.44 $ 21.04 Net income, per dilu

Exhibit 99.1 For Immediate Release United Therapeutics Corporation Reports Fourth Quarter and Full Year 2024 Financial Results SILVER SPRING, Md. and RESEARCH TRIANGLE PARK, N.C., February 26, 2025: United Therapeutics Corporation (Nasdaq: UTHR), a public benefit corporation, today announced its financial results for the quarter and year ended December 31, 2024. Full year 2024 revenues rose to a r

February 10, 2025 EX-99

JOINT FILING AGREEMENT

JOINT FILING AGREEMENT The undersigned hereby agree that this Schedule 13G (the “Schedule 13G”) with respect to the common stock of United Therapeutics Corporation is, and any additional amendment thereto signed by each of the undersigned shall be, filed on behalf of each undersigned pursuant to and in accordance with the provisions of 13d-1(k) under the Securities Exchange Act of 1934, as amended, and that all subsequent amendments to the Schedule 13G shall be filed on behalf of each of the undersigned without the necessity of filing additional joint filing agreements.

January 13, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 13, 2025 United Therapeu

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 13, 2025 United Therapeutics Corporation (Exact Name of Registrant as Specified in its Charter) Delaware 000-26301 52-1984749 (State or Other (Commission (I.R.S. Employer Jur

January 13, 2025 EX-99.1

United Therapeutics: Enabling Inspiration J.P. MORGAN HEALTHCARE CONFERENCE JANUARY 13, 2025 2 INTRODUCTION Safe Harbor Statement MIROKIDNEY®, MIROLIVERELAP®, ORENITRAM®, REMODULIN®, TYVASO®, and TYVASO DPI® are registered trademarks of United Therap

Exhibit 99.1 United Therapeutics: Enabling Inspiration J.P. MORGAN HEALTHCARE CONFERENCE JANUARY 13, 2025 2 INTRODUCTION Safe Harbor Statement MIROKIDNEY®, MIROLIVERELAP®, ORENITRAM®, REMODULIN®, TYVASO®, and TYVASO DPI® are registered trademarks of United Therapeutics Corporation and/or its subsidiaries. UHEART™, UKIDNEY™, ULOBE™, ULUNG™, and UTHYMOKIDNEY™ are trademarks of United Therapeutics Co

November 8, 2024 SC 13G/A

UTHR / United Therapeutics Corporation / ROTHBLATT MARTINE A - SC 13G/A Passive Investment

SC 13G/A 1 tm2427864d1sc13ga.htm SC 13G/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 13G (Rule 13d-102) Information to be Included in Statements Filed Pursuant to § 240.13d-1(b), (c) and (d) and Amendments Thereto Filed Pursuant to § 240.13d-2 Under the Securities Exchange Act of 1934 (Amendment No. 6) United Therapeutics Corporation (Name of Issuer) Common Stoc

October 30, 2024 EX-99.1

Three Months Ended September 30, Dollar Change Percentage Change 2024 2023 Total revenues $ 748.9 $ 609.4 $ 139.5 23 % Net income $ 309.1 $ 267.6 $ 41.5 16 % Net income, per basic share $ 6.93 $ 5.71 $ 1.22 21 % Net income, per diluted share $ 6.39 $

Exhibit 99.1 For Immediate Release United Therapeutics Corporation Reports Third Quarter 2024 Financial Results SILVER SPRING, Md. and RESEARCH TRIANGLE PARK, N.C., October 30, 2024: United Therapeutics Corporation (Nasdaq: UTHR), a public benefit corporation, today announced its financial results for the quarter ended September 30, 2024. Total revenues in the third quarter of 2024 grew 23 percent

October 30, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934. For the quarterly period ended September 30, 2024 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934. For the transition period from to Commission file num

October 30, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 30, 2024 United Therapeu

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 30, 2024 United Therapeutics Corporation (Exact Name of Registrant as Specified in Charter) Delaware 000-26301 52-1984749 (State or Other Jurisdiction of Incorporation) (Comm

October 16, 2024 SC 13G

UTHR / United Therapeutics Corporation / STATE STREET CORP Passive Investment

SC 13G 1 UnitedTherapeuticsCorp.htm SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* UNITED THERAPEUTICS CORP (Name of Issuer) COMMON STOCK (Title of Class of Securities) 91307C102 (CUSIP Number) September 30, 2024 (Date of Event Which Requires Filing of This Statement) Check the appropriate box to designate the rule

July 31, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934. For the quarterly period ended June 30, 2024 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934. For the transition period from to Commission file number 0

July 31, 2024 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 31, 2024 United Therapeutics Corporation (Exact Name of Registrant as Specified in Charter) Delaware 000-26301 52-1984749 (State or Other Jurisdiction of Incorporation) (Commiss

July 31, 2024 EX-99.1

Three Months Ended June 30, Dollar Change Percentage Change 2024 2023 Total revenues $ 714.9 $ 596.5 $ 118.4 20 % Net income $ 278.1 $ 259.2 $ 18.9 7 % Net income, per basic share $ 6.26 $ 5.53 $ 0.73 13 % Net income, per diluted share $ 5.85 $ 5.24

Exhibit 99.1 For Immediate Release United Therapeutics Corporation Reports Second Quarter 2024 Financial Results SILVER SPRING, Md. and RESEARCH TRIANGLE PARK, N.C., July 31, 2024: United Therapeutics Corporation (Nasdaq: UTHR), a public benefit corporation, today announced its financial results for the quarter ended June 30, 2024. Total revenues in the second quarter of 2024 grew 20 percent year-

July 31, 2024 EX-10.2

eventh Amendment to Specialty Pharmacy Network Agreement, dated as of June 7, 2024, between the Registrant and Accredo Health Group, Inc.

Exhibit 10.2 SEVENTH AMENDMENT TO SPECIALTY PHARMACY NETWORK AGREEMENT This Seventh Amendment to Specialty Pharmacy Network Agreement (this “Amendment”) is made as of the date the last Party executes this Amendment (the “Amendment Effective Date”), by and between Accredo Health Group, Inc. (“Specialty Pharmacy”), and United Therapeutics Corporation (“UT”). Specialty Pharmacy and UT are each referr

July 31, 2024 EX-10.3

fth Amendment to Wholesale Product Purchase Agreement, dated as of Jun

Exhibit 10.3 Twelfth Amendment To Wholesale Product Purchase Agreement THIS TWELFTH AMENDMENT TO WHOLESALE PRODUCT PURCHASE AGREEMENT (this “Twelfth Amendment”) is made as of the date the last Party executes this Twelfth Amendment (the “Amendment Effective Date”), by and between Priority Healthcare Distribution, Inc., doing business as CuraScript SD Specialty Distribution, a Florida corporation ha

July 31, 2024 EX-FILING FEES

Filing Fee Table*

Exhibit 107 CALCULATION OF FILING FEE TABLES Form S-8 (Form Type) United Therapeutics Corporation (Exact Name of Registrant as Specified in its Charter) TABLE 1 – NEWLY REGISTERED SECURITIES Security Type Security Class Title Fee Calculation Rule Amount Registered(1) Proposed Maximum Offering Price Per Unit(2) Maximum Aggregate Offering Price(2) Fee Rate Amount of Registration Fee Equity Common Stock, par value $0.

July 31, 2024 S-8

As filed with the Securities and Exchange Commission on July 31, 2024

As filed with the Securities and Exchange Commission on July 31, 2024 Registration No.

June 27, 2024 EX-10.1

nited Therapeutics Corporation Amended and Restated 2015 Stock Incentive Plan, incorporated by reference to Exhibit 10.1 to the Registrant’s Current Report on Form 8-K filed June 27, 2024

Exhibit 10.1 UNITED THERAPEUTICS CORPORATION AMENDED AND RESTATED 2015 STOCK INCENTIVE PLAN (effective June 26, 2024) 1. Purpose The purpose of the United Therapeutics Corporation Amended and Restated 2015 Stock Incentive Plan (this “Plan”) is to advance the interests of United Therapeutics Corporation (the “Company”) by stimulating the efforts of employees, officers, non-employee directors and ot

June 27, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 26, 2024 United Therapeutic

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 26, 2024 United Therapeutics Corporation (Exact Name of Registrant as Specified in its Charter) Delaware 000-26301 52-1984749 (State or Other (Commission (I.R.S. Employer Jurisd

June 27, 2024 EX-99.1

For Immediate Release

Exhibit 99.1 For Immediate Release United Therapeutics Corporation Announces Election of Jan Malcolm to its Board of Directors SILVER SPRING, Md. and RESEARCH TRIANGLE PARK, N.C., June 27, 2024: United Therapeutics Corporation (Nasdaq: UTHR), a public benefit corporation, announced the addition of former Minnesota Commissioner of Health Jan Malcolm to its Board of Directors. Ms. Malcolm was electe

June 10, 2024 SC 13G/A

UTHR / United Therapeutics Corporation / VANGUARD GROUP INC - SCHEDULE 13G/A Passive Investment

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Schedule 13G Under the Securities Exchange Act of 1934 (Amendment No.: 12)* Name of issuer: United Therapeutics Corp Title of Class of Securities: Common Stock CUSIP Number: 91307C102 Date of Event Which Requires Filing of this Statement: May 31, 2024 Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

May 31, 2024 SD

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM SD SPECIALIZED DISCLOSURE REPORT United Therapeutics Corporation (Exact Name of Registrant as Specified in Charter)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM SD SPECIALIZED DISCLOSURE REPORT United Therapeutics Corporation (Exact Name of Registrant as Specified in Charter) Delaware 000-26301 52-1984749 (State or Other (Commission (I.R.S. Employer Jurisdiction of File Number) Identification Number) Incorporation or Organization) 1000 Spring Street Silver Spring, MD 20910 (Addre

May 1, 2024 EX-99.1

Three Months Ended March 31, Dollar Change Percentage Change 2024 2023 Total revenues $ 677.7 $ 506.9 $ 170.8 34 % Net income $ 306.6 $ 240.9 $ 65.7 27 % Net income, per basic share $ 6.52 $ 5.20 $ 1.32 25 % Net income, per diluted share $ 6.17 $ 4.8

Exhibit 99.1 For Immediate Release United Therapeutics Corporation Reports First Quarter 2024 Financial Results SILVER SPRING, Md. and RESEARCH TRIANGLE PARK, N.C., May 1, 2024: United Therapeutics Corporation (Nasdaq: UTHR), a public benefit corporation, today announced its financial results for the quarter ended March 31, 2024. Total revenues in the first quarter of 2024 grew 34 percent year-ove

May 1, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934. For the quarterly period ended March 31, 2024 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934. For the transition period from to Commission file number

May 1, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 1, 2024 United Therapeutics

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 1, 2024 United Therapeutics Corporation (Exact Name of Registrant as Specified in Charter) Delaware 000-26301 52-1984749 (State or Other Jurisdiction of Incorporation) (Commissio

April 29, 2024 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant x Filed by a Party other than the Registran

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant x Filed by a Party other than the Registrant o Check the appropriate box: o Preliminary Proxy Statement o Confidential, for Use of the Commission Only (as permitted by Rule 14a‑6(e)(2)) o Defin

April 29, 2024 DEF 14A

DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant x Filed by a Party other than the Registrant o Check the appropriate box: o Preliminary Proxy Statement o Confidential, for Use of the Commission Only (as permitted by Rule 14a‑6(e)(2)) x Defin

April 29, 2024 DEF 14A

DEFINITIVE PROXY STATEMENT

About United Therapeutics Our company was founded over 27 years ago with the challenge of finding a way to cure or treat a rare, life-threatening illness suffered by our CEO's daughter.

March 29, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 29, 2024 United Therapeuti

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 29, 2024 United Therapeutics Corporation (Exact Name of Registrant as Specified in its Charter) Delaware 000-26301 52-1984749 (State or Other (Commission (I.R.S. Employer Juris

March 25, 2024 EX-99.1

For Immediate Release

Exhibit 99.1 For Immediate Release United Therapeutics Corporation Announces $1 Billion Accelerated Share Repurchase Program Repurchase reflects the strength of United Therapeutics’ balance sheet and confidence in its near-term prospects SILVER SPRING, Md. and RESEARCH TRIANGLE PARK, N.C., March 25, 2024: United Therapeutics Corporation (Nasdaq: UTHR), a public benefit corporation, today announced

March 25, 2024 EX-10.1

Master Confirmation – Accelerated Share Repurchase, between the Company and Citi, dated March 25, 2024

Exhibit 10.1 EXECUTION VERSION United Therapeutics Corporation 1000 Spring Street Silver Spring MD 20910 Attention: James Edgemond, Chief Financial Officer and Treasurer Re: Accelerated Share Repurchase Ladies and Gentlemen: This master confirmation (this “Master Confirmation”), dated as of March 25, 2024 is intended to set forth certain terms and provisions of certain Transactions (each, a “Trans

March 25, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 25, 2024 United Therapeuti

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 25, 2024 United Therapeutics Corporation (Exact Name of Registrant as Specified in its Charter) Delaware 000-26301 52-1984749 (State or Other (Commission (I.R.S. Employer Juris

February 27, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 26, 2024 United Therape

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 26, 2024 United Therapeutics Corporation (Exact Name of Registrant as Specified in Charter) Delaware 000-26301 52-1984749 (State or Other (Commission (I.R.S. Employer Jurisd

February 21, 2024 EX-97

cs Corporation Clawback Poli

Exhibit 97 UNITED THERAPEUTICS CORPORATION CLAWBACK POLICY Adopted July 12, 2023 Recoupment of Incentive-Based Compensation It is the policy of United Therapeutics Corporation (the “Company”) that, in the event the Company is required to prepare an accounting restatement of the Company’s consolidated financial statements (including any required accounting restatement to correct an error in previou

February 21, 2024 EX-99.2

For Immediate Release

Exhibit 99.2 For Immediate Release United Therapeutics Commences Litigation to Ensure Fairness in the Drug Review Process SILVER SPRING, Md., and RESEARCH TRIANGLE PARK, N.C., February 21, 2024 - United Therapeutics Corporation (Nasdaq: UTHR) announced today the commencement of litigation with the United States Food and Drug Administration (FDA). In the litigation, United Therapeutics alleges that

February 21, 2024 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K (Mark One) ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934. For the fiscal year ended December 31, 2023 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934. For the transition period from to Commission file number 0-26301 United Therapeu

February 21, 2024 EX-4.2

Description of Securities Registered under Section 12 of the Exchange Act

Exhibit 4.2 DESCRIPTION OF THE REGISTRANT’S SECURITIES REGISTERED PURSUANT TO SECTION 12 OF THE SECURITIES EXCHANGE ACT OF 1934 United Therapeutics Corporation has one class of securities registered under Section 12 of the Securities Exchange Act of 1934, as amended (the Exchange Act): Common Stock, par value $0.01 per share (common stock). All references in this document to United Therapeutics, o

February 21, 2024 EX-10.59

Sixth Amendment to Specialty Pharmacy Network Agreement, dated as of November 7, 2023, between the Registrant and Accredo Health Group, Inc.

Exhibit 10.59 SIXTH AMENDMENT TO SPECIALTY PHARMACY NETWORK AGREEMENT This Sixth Amendment to Specialty Pharmacy Network Agreement (this “Amendment”) is made as of the date the last Party executes this Amendment (the “Amendment Effective Date”), by and between Accredo Health Group, Inc. (“Specialty Pharmacy”), and United Therapeutics Corporation (“UT”). Specialty Pharmacy and UT are each referred

February 21, 2024 EX-99.1

Three Months Ended December 31, Year Ended December 31, 2023 2022 2023 2022 Total revenues $ 614.7 $ 491.5 $ 2,327.5 $ 1,936.3 Net income $ 217.1 $ 132.1 $ 984.8 $ 727.3 Net income, per basic share $ 4.62 $ 2.88 $ 21.04 $ 15.98 Net income, per dilute

Exhibit 99.1 For Immediate Release United Therapeutics Corporation Reports Fourth Quarter and Full Year 2023 Financial Results SILVER SPRING, Md. and RESEARCH TRIANGLE PARK, N.C., February 21, 2024: United Therapeutics Corporation (Nasdaq: UTHR), a public benefit corporation, today announced its financial results for the quarter and year ended December 31, 2023. Full year 2023 revenues rose to a r

February 21, 2024 EX-21

Subsidiaries of the Registrant.

Exhibit 21 SUBSIDIARIES OF THE REGISTRANT IVIVA Medical, Inc., a Delaware corporation Lung Bioengineering Inc., a Delaware corporation Lung Biotechnology PBC, a Delaware public benefit corporation Miromatrix Medical Inc., a Delaware corporation Revivicor, Inc., a Delaware corporation United Therapeutics Europe, Ltd., a company incorporated under the laws of England and Wales United Therapeutics Ir

February 21, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 21, 2024 United Therape

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 21, 2024 United Therapeutics Corporation (Exact Name of Registrant as Specified in Charter) Delaware 000-26301 52-1984749 (State or Other Jurisdiction of Incorporation) (Com

February 21, 2024 EX-10.52

Eleventh Amendment to Wholesale Product Purchase Agreement, dated as of November 3, 2023, by and between Priority Healthcare Distribution, Inc., doing business as CuraScript SD Specialty Distribution, and the Registrant

Exhibit 10.52 Certain information (marked as [***]) has been excluded from this exhibit because it is both (i) not material and (ii) would be competitively harmful if publicly disclosed. Eleventh Amendment To Wholesale Product Purchase Agreement This Eleventh Amendment to Wholesale Product Purchase Agreement (this “Eleventh Amendment”) is made as of the date the last Party executes this Eleventh A

February 14, 2024 SC 13G/A

UTHR / United Therapeutics Corporation / Avoro Capital Advisors LLC - UNITED THERAPEUTICS CORPORATION Passive Investment

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No. 3)* United Therapeutics Corporation (Name of Issuer) Common Stock, par value $0.01 per share (Title of Class of Securities) 91307C102 (CUSIP Number) December 31, 2023 (Date of Event Which Requires Filing of This Statement) Check the appropriate box to designate the rule

February 14, 2024 SC 13G/A

UTHR / United Therapeutics Corporation / ROTHBLATT MARTINE A - SC 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 13G (Rule 13d-102) Information to be Included in Statements Filed Pursuant to § 240.

February 13, 2024 SC 13G/A

UTHR / United Therapeutics Corporation / VANGUARD GROUP INC - SCHEDULE 13G/A Passive Investment

SC 13G/A 1 tv02159-unitedtherapeuticsco.htm SCHEDULE 13G/A SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Schedule 13G Under the Securities Exchange Act of 1934 (Amendment No.: 11)* Name of issuer: United Therapeutics Corp Title of Class of Securities: Common Stock CUSIP Number: 91307C102 Date of Event Which Requires Filing of this Statement: December 29, 2023 Check the appropriate box

February 8, 2024 SC 13G/A

CELU / Celularity Inc. / UNITED THERAPEUTICS Corp - SC 13G/A Passive Investment

SC 13G/A 1 tm245374d1sc13ga.htm SC 13G/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 13G (Rule 13d-102) Information to be Included in Statements Filed Pursuant to § 240.13d-1(b), (c) and (d) and Amendments Thereto Filed Pursuant to § 240.13d-2 Under the Securities Exchange Act of 1934 (Amendment No. 2 ) Celularity Inc. (Name of Issuer) Common Stock, $0.0001 par v

February 8, 2024 SC 13G/A

UTHR / United Therapeutics Corporation / WELLINGTON MANAGEMENT GROUP LLP - SEC SCHEDULE 13G Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 2 )* UNITED THERAPEUTICS Corp (Name of Issuer) Common Stock (Title of Class of Securities) 91307C102 (CUSIP Number) December 29, 2023 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which th

December 22, 2023 SC 13D

MIRO / Miromatrix Medical Inc / UNITED THERAPEUTICS Corp - SC 13D Activist Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 Miromatrix Medical Inc. (Name of Issuer) Common Stock, par value $0.01 per share (Title of Class of Securities) 60471P108 (CUSIP Number) John S. Hess, Jr., Esq. Executive Vice President and Deputy General Counsel United Therapeutics Corporation 1735 Connecticut Avenue, N.W

December 20, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 20, 2023 United Therape

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 20, 2023 United Therapeutics Corporation (Exact Name of Registrant as Specified in its Charter) Delaware 000-26301 52-1984749 (State or Other (Commission (I.R.S. Employer Ju

December 13, 2023 EX-99.(A)(5)(E)

Joint Press Release issued on December 13, 2023.

Exhibit (a)(5)(E) For Immediate Release United Therapeutics and Miromatrix Medical Announce Completion of Tender Offer and Merger SILVER SPRING, Md.

December 13, 2023 CORRESP

Abu Dhabi · Beijing · Brussels · Century City · Dallas · Denver · Dubai · Frankfurt · Hong Kong · Houston · London · Los Angeles Munich · New York · Orange County · Palo Alto · Paris · Riyadh · San Francisco · Singapore · Washington, D.C.

Gibson, Dunn & Crutcher LLP 1050 Connecticut Avenue, N.W. Washington, D.C. 20036-5306 Tel 202.955.8500 gibsondunn.com Stephen Glover Direct: +1 202.955.8593 Fax: +1 202.530.9598 [email protected] VIA EDGAR December 13, 2023 Brian Soares, Special Counsel Christina Chalk, Assistant Chief U.S. Securities and Exchange Commission Division of Corporation Finance Office of Mergers & Acquisitions 10

December 13, 2023 SC TO-T/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE TO TENDER OFFER STATEMENT UNDER SECTION 14(D)(1) OR 13(E)(1) OF THE SECURITIES EXCHANGE ACT OF 1934 (AMENDMENT NO. 3) MIROMATRIX MEDICAL INC. (Name of Subject Company —

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE TO TENDER OFFER STATEMENT UNDER SECTION 14(D)(1) OR 13(E)(1) OF THE SECURITIES EXCHANGE ACT OF 1934 (AMENDMENT NO. 3) MIROMATRIX MEDICAL INC. (Name of Subject Company — Issuer) MORPHEUS SUBSIDIARY INC. a wholly owned subsidiary of UNITED THERAPEUTICS CORPORATION (Names of Filing Persons — Offerors) Common Stock, par v

December 12, 2023 SC TO-T/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE TO TENDER OFFER STATEMENT UNDER SECTION 14(D)(1) OR 13(E)(1) OF THE SECURITIES EXCHANGE ACT OF 1934 (AMENDMENT NO. 2) MIROMATRIX MEDICAL INC. (Name of Subject Company —

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE TO TENDER OFFER STATEMENT UNDER SECTION 14(D)(1) OR 13(E)(1) OF THE SECURITIES EXCHANGE ACT OF 1934 (AMENDMENT NO. 2) MIROMATRIX MEDICAL INC. (Name of Subject Company — Issuer) MORPHEUS SUBSIDIARY INC. a wholly owned subsidiary of UNITED THERAPEUTICS CORPORATION (Names of Filing Persons — Offerors) Common Stock, par v

December 12, 2023 EX-99.(A)(5)(D)

Joint Press Release issued on December 12, 2023.

Exhibit (a)(5)(D) For Immediate Release United Therapeutics and Miromatrix Medical Announce Successful Tender Offer SILVER SPRING, Md.

December 4, 2023 SC TO-T/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE TO TENDER OFFER STATEMENT UNDER SECTION 14(D)(1) OR 13(E)(1) OF THE SECURITIES EXCHANGE ACT OF 1934 (AMENDMENT NO. 1) MIROMATRIX MEDICAL INC. (Name of Subject Company —

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE TO TENDER OFFER STATEMENT UNDER SECTION 14(D)(1) OR 13(E)(1) OF THE SECURITIES EXCHANGE ACT OF 1934 (AMENDMENT NO. 1) MIROMATRIX MEDICAL INC. (Name of Subject Company — Issuer) MORPHEUS SUBSIDIARY INC. a wholly owned subsidiary of UNITED THERAPEUTICS CORPORATION (Names of Filing Persons — Offerors) Common Stock, par v

December 4, 2023 EX-FILING FEES

Filing Fee Table

Exhibit 107 Calculation of Filing Fee Table SCHEDULE TO-T (Rule 14d-100) Miromatrix Medical Inc.

November 29, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 27, 2023 United Therape

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 27, 2023 United Therapeutics Corporation (Exact Name of Registrant as Specified in its Charter) Delaware 000-26301 52-1984749 (State or Other (Commission (I.R.S. Employer Ju

November 13, 2023 EX-99.(A)(1)(F)

on November 13, 2023 (incorporated by reference to Exhibit (a)(1)(F) to the Schedule TO filed November 13, 2023).

Exhibit (a)(1)(F) This announcement is neither an offer to purchase nor a solicitation of an offer to sell Shares (as defined below).

November 13, 2023 EX-99.(A)(1)(C)

Form of Notice of Guaranteed Delivery.

 Exhibit (a)(1)(C) NOTICE OF GUARANTEED DELIVERY for Tender of Common Shares of MIROMATRIX MEDICAL INC.

November 13, 2023 EX-99.(A)(1)(D)

Form of Letter to Brokers, Dealers, Commercial Banks, Trust Companies and Other Nominees.*

 Exhibit (a)(1)(D) Offer to Purchase All Outstanding Shares of Common Stock of MIROMATRIX MEDICAL INC.

November 13, 2023 EX-FILING FEES

Filing Fee Table*

Exhibit 107 Calculation of Filing Fee Table SCHEDULE TO-T (Rule 14d-100) Miromatrix Medical Inc.

November 13, 2023 SC TO-T

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE TO TENDER OFFER STATEMENT UNDER SECTION 14(D)(1) OR 13(E)(1) OF THE SECURITIES EXCHANGE ACT OF 1934 MIROMATRIX MEDICAL INC. (Name of Subject Company — Issuer) MORPHEUS S

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE TO TENDER OFFER STATEMENT UNDER SECTION 14(D)(1) OR 13(E)(1) OF THE SECURITIES EXCHANGE ACT OF 1934 MIROMATRIX MEDICAL INC. (Name of Subject Company — Issuer) MORPHEUS SUBSIDIARY INC. a wholly owned subsidiary of UNITED THERAPEUTICS CORPORATION (Names of Filing Persons — Offerors) Common Stock, par value $0.00001 per

November 13, 2023 EX-99.(A)(1)(B)

Form of Letter of Transmittal (including Internal Revenue Service Form W-9).

 Exhibit (a)(1)(B) Letter of Transmittal to Tender Shares of Common Stock of MIROMATRIX MEDICAL INC.

November 13, 2023 EX-99.(A)(1)(E)

Form of Letter to Clients for use by Brokers, Dealers, Commercial Banks, Trust Companies and Other Nominees.*

 Exhibit (a)(1)(E) Offer to Purchase All Outstanding Shares of Common Stock of MIROMATRIX MEDICAL INC.

November 13, 2023 EX-99.(A)(1)(A)

Offer to Purchase, dated November 13, 2023.

TABLE OF CONTENTS  Exhibit (a)(1)(A) Offer to Purchase All Outstanding Shares of Common Stock of MIROMATRIX MEDICAL INC.

November 1, 2023 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934. For the quarterly period ended September 30, 2023 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934. For the transition period from to Commission file num

November 1, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 1, 2023 United Therapeu

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 1, 2023 United Therapeutics Corporation (Exact Name of Registrant as Specified in Charter) Delaware 000-26301 52-1984749 (State or Other Jurisdiction of Incorporation) (Comm

November 1, 2023 EX-10.1

, 2023, between the Registrant and Accredo Health Group, Inc., incorporated by reference to Exhibit 10.

Exhibit 10.1 FIFTH AMENDMENT TO SPECIALTY PHARMACY NETWORK AGREEMENT This Fifth Amendment to Specialty Pharmacy Network Agreement (this “Amendment”) is made as of the date the last Party executes this Amendment (the “Amendment Effective Date”), by and between Accredo Health Group, Inc. (“Specialty Pharmacy”), and United Therapeutics Corporation (“UT”). Specialty Pharmacy and UT are each referred t

November 1, 2023 EX-99.1

Three Months Ended September 30, Dollar Change Percentage Change 2023 2022 Total revenues $ 609.4 $ 516.0 $ 93.4 18 % Net income $ 267.6 $ 239.3 $ 28.3 12 % Net income, per basic share $ 5.71 $ 5.26 $ 0.45 9 % Net income, per diluted share $ 5.38 $ 4

Exhibit 99.1 For Immediate Release United Therapeutics Corporation Reports Third Quarter 2023 Financial Results SILVER SPRING, Md. and RESEARCH TRIANGLE PARK, N.C., November 1, 2023: United Therapeutics Corporation (Nasdaq: UTHR), a public benefit corporation, today announced its financial results for the quarter ended September 30, 2023. Total revenues in the third quarter of 2023 grew 18% year-o

November 1, 2023 SC TO-C

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE TO TENDER OFFER STATEMENT UNDER SECTION 14(D)(1) OR 13(E)(1) OF THE SECURITIES EXCHANGE ACT OF 1934 Miromatrix Medical Inc. (Name of Subject Company — Issuer) Morpheus S

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE TO TENDER OFFER STATEMENT UNDER SECTION 14(D)(1) OR 13(E)(1) OF THE SECURITIES EXCHANGE ACT OF 1934 Miromatrix Medical Inc. (Name of Subject Company — Issuer) Morpheus Subsidiary Inc. a wholly owned subsidiary of United Therapeutics Corporation (Names of Filing Persons — Offerors) Common Stock, par value $0.00001 per

November 1, 2023 EX-99.1

Excerpts from Transcript of United Therapeutics Corporation’s Q3 Earning Call held on November 1, 2023 (incorporated by reference to Exhibit 99.1 to the Schedule TO-C filed by United Therapeutics Corporation with the SEC on November 1, 2023).

Exhibit 99.1 The following are excerpts from the transcript of United Therapeutics’ Q3 2023 earnings call held on November 1, 2023: Martine Rothblatt, Ph.D., Chairperson and Chief Executive Officer: Also, earlier this week, we announced an agreement to acquire publicly traded Miromatrix Medical, a company focused on ending the waiting list for organ transplantation. Miromatrix utilizes an organ ma

October 30, 2023 EX-99.1

Joint press release issued by United Therapeutics Corporation and Miromatrix Medical Inc., dated October 30, 2023 (incorporated by reference to Exhibit 99.1 to the Schedule TO-C filed by United Therapeutics Corporation with the SEC on October 30, 2023).

Exhibit 99.1 For Immediate Release United Therapeutics to Acquire Miromatrix Medical SILVER SPRING, Md., RESEARCH TRIANGLE PARK, N.C., and EDEN PRAIRIE, Minn., October 30, 2023 - United Therapeutics Corporation (Nasdaq: UTHR) and Miromatrix Medical Inc. (Nasdaq: MIRO) announced today a definitive agreement for United Therapeutics to acquire Miromatrix. Miromatrix is a life sciences company focused

October 30, 2023 SC TO-C

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE TO TENDER OFFER STATEMENT UNDER SECTION 14(D)(1) OR 13(E)(1) OF THE SECURITIES EXCHANGE ACT OF 1934 Miromatrix Medical Inc. (Name of Subject Company — Issuer) Morpheus S

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE TO TENDER OFFER STATEMENT UNDER SECTION 14(D)(1) OR 13(E)(1) OF THE SECURITIES EXCHANGE ACT OF 1934 Miromatrix Medical Inc. (Name of Subject Company — Issuer) Morpheus Subsidiary Inc. a wholly owned subsidiary of United Therapeutics Corporation (Names of Filing Persons — Offerors) Common Stock, par value $0.00001 per

October 30, 2023 EX-99.1

United Therapeutics Corporation Investor FAQ, dated October 30, 2023 (incorporated by reference to Exhibit 99.1 to the Schedule TO-C filed by United Therapeutics Corporation with the SEC on October 30, 2023)

Exhibit 99.1 United Therapeutics Investor FAQ Pending Acquisition of Miromatrix Medical, Inc. October 30, 2023 Why is United Therapeutics acquiring Miromatrix? Miromatrix is another shot on goal for our objective of creating an unlimited supply of tolerable, transplantable organs. This transaction would complement our capabilities in the organ manufacturing space and expand our early-stage pipelin

October 30, 2023 SC TO-C

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE TO TENDER OFFER STATEMENT UNDER SECTION 14(D)(1) OR 13(E)(1) OF THE SECURITIES EXCHANGE ACT OF 1934 Miromatrix Medical Inc. (Name of Subject Company — Issuer) Morpheus S

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE TO TENDER OFFER STATEMENT UNDER SECTION 14(D)(1) OR 13(E)(1) OF THE SECURITIES EXCHANGE ACT OF 1934 Miromatrix Medical Inc. (Name of Subject Company — Issuer) Morpheus Subsidiary Inc. a wholly owned subsidiary of United Therapeutics Corporation (Names of Filing Persons — Offerors) Common Stock, par value $0.00001 per

August 2, 2023 EX-99.1

Three Months Ended June 30, Dollar Change Percentage Change 2023 2022 Total revenues $ 596.5 $ 466.9 $ 129.6 28 % Net income $ 259.2 $ 116.0 $ 143.2 123 % Net income, per basic share $ 5.53 $ 2.56 $ 2.97 116 % Net income, per diluted share $ 5.24 $ 2

Exhibit 99.1 For Immediate Release United Therapeutics Corporation Reports Second Quarter 2023 Financial Results SILVER SPRING, Md. and RESEARCH TRIANGLE PARK, N.C., August 2, 2023: United Therapeutics Corporation (Nasdaq: UTHR), a public benefit corporation, today announced its financial results for the quarter ended June 30, 2023. Total revenues in the second quarter of 2023 grew 28% year-over-y

August 2, 2023 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 2, 2023 United Therapeutics Corporation (Exact Name of Registrant as Specified in Charter) Delaware 000-26301 52-1984749 (State or Other Jurisdiction of Incorporation) (Commis

August 2, 2023 S-8

As filed with the Securities and Exchange Commission on August 2, 2023

As filed with the Securities and Exchange Commission on August 2, 2023 Registration No.

August 2, 2023 EX-10.2

, 2023, between the Registrant and Accredo Health Group, Inc., incorporated by reference to Exhibit 10.2 to the Registrant’s Quarterly Report on Form 10-Q for the quarter ended

Exhibit 10.2 FOURTH AMENDMENT TO SPECIALTY PHARMACY NETWORK AGREEMENT This Fourth Amendment to Specialty Pharmacy Network Agreement (this “Amendment”) is made as of the date the last Party executes this Amendment (the “Amendment Effective Date”), by and between Accredo Health Group, Inc. (“Specialty Pharmacy”), and United Therapeutics Corporation (“UT”). Specialty Pharmacy and UT are each referred

August 2, 2023 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934. For the quarterly period ended June 30, 2023 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934. For the transition period from to Commission file number 0

August 2, 2023 EX-FILING FEES

Filing Fee Table*

Exhibit 107 CALCULATION OF FILING FEE TABLES Form S-8 (Form Type) United Therapeutics Corporation (Exact Name of Registrant as Specified in its Charter) TABLE 1 – NEWLY REGISTERED SECURITIES Security Type Security Class Title Fee Calculation Rule Amount Registered(1) Proposed Maximum Offering Price Per Unit(3) Maximum Aggregate Offering Price(3) Fee Rate Amount of Registration Fee Equity Common Stock, par value $0.

July 24, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 24, 2023 United Therapeutic

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 24, 2023 United Therapeutics Corporation (Exact Name of Registrant as Specified in its Charter) Delaware 000-26301 52-1984749 (State or Other (Commission (I.R.S. Employer Jurisd

July 24, 2023 EX-99.1

For Immediate Release

Exhibit 99.1 For Immediate Release United Therapeutics Wins Appeal in Dry Powder Inhaler Patent Litigation SILVER SPRING, Md. and RESEARCH TRIANGLE PARK, N.C., July 24, 2023 - United Therapeutics Corporation (Nasdaq: UTHR), a public benefit corporation, announced today that the United States Court of Appeals for the Federal Circuit affirmed the district court decision in the patent litigation Unit

July 14, 2023 8-K/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K/A (Amendment No. 1) CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 26, 202

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K/A (Amendment No. 1) CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 26, 2023 United Therapeutics Corporation (Exact Name of Registrant as Specified in its Charter) Delaware 000-26301 52-1984749 (State or Other (Commission (I.

July 10, 2023 SC 13G/A

UTHR / United Therapeutics Corp / WELLINGTON MANAGEMENT GROUP LLP - SEC SCHEDULE 13G Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 1 )* UNITED THERAPEUTICS Corp (Name of Issuer) Common Stock (Title of Class of Securities) 91307C102 (CUSIP Number) June 30, 2023 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which this S

June 28, 2023 EX-10.1

United Therapeutics Corporation Amended and Restated 2015 Stock Incentive Plan

Exhibit 10.1 UNITED THERAPEUTICS CORPORATION AMENDED AND RESTATED 2015 STOCK INCENTIVE PLAN (effective June 26, 2023) 1. Purpose The purpose of the United Therapeutics Corporation Amended and Restated 2015 Stock Incentive Plan (this “Plan”) is to advance the interests of United Therapeutics Corporation (the “Company”) by stimulating the efforts of employees, officers, non-employee directors and ot

June 28, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 26, 2023 United Therapeutic

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 26, 2023 United Therapeutics Corporation (Exact Name of Registrant as Specified in its Charter) Delaware 000-26301 52-1984749 (State or Other (Commission (I.R.S. Employer Jurisd

May 31, 2023 SD

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM SD SPECIALIZED DISCLOSURE REPORT United Therapeutics Corporation (Exact Name of Registrant as Specified in Charter)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM SD SPECIALIZED DISCLOSURE REPORT United Therapeutics Corporation (Exact Name of Registrant as Specified in Charter) Delaware 000-26301 52-1984749 (State or Other (Commission (I.R.S. Employer Jurisdiction of File Number) Identification Number) Incorporation or Organization) 1040 Spring Street Silver Spring, MD 20910 (Addre

May 3, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 3, 2023 United Therapeutics

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 3, 2023 United Therapeutics Corporation (Exact Name of Registrant as Specified in Charter) Delaware 000-26301 52-1984749 (State or Other Jurisdiction of Incorporation) (Commissio

May 3, 2023 EX-10.1

, by and between Priority Healthcare Distribution, Inc., doing business as CuraScript SD Specialty Distribution, and the Registrant, incorporated by reference to Exhibit 10.

Exhibit 10.1 Tenth Amendment To Wholesale Product Purchase Agreement This Tenth Amendment to Wholesale Product Purchase Agreement (this “Tenth Amendment” is made as of the date the last Party executes this Tenth Amendment (the “Amendment Effective Date”), by and between Priority Healthcare Distribution, Inc., doing business as CuraScript SD Specialty Distribution, a Florida corporation having offi

May 3, 2023 EX-10.2

, between the Registrant and Accredo Health Group, Inc., incorporated by reference to Exhibit 10.

Exhibit 10.2 THIRD AMENDMENT TO SPECIALTY PHARMACY NETWORK AGREEMENT This Third Amendment to Specialty Pharmacy Network Agreement (this “Amendment”) is made as of the date the last Party executes this Amendment (the “Amendment Effective Date”), by and between Accredo Health Group, Inc. (“Specialty Pharmacy”), and United Therapeutics Corporation (“UT”). Specialty Pharmacy and UT are each referred t

May 3, 2023 EX-99.1

UNITED THERAPEUTICS CORPORATION REPORTS FIRST QUARTER 2023 FINANCIAL RESULTS

Exhibit 99.1 For Immediate Release UNITED THERAPEUTICS CORPORATION REPORTS FIRST QUARTER 2023 FINANCIAL RESULTS SILVER SPRING, Md. and RESEARCH TRIANGLE PARK, N.C., May 3, 2023: United Therapeutics Corporation (Nasdaq: UTHR), a public benefit corporation, today announced its financial results for the quarter ended March 31, 2023. Total revenues in the first quarter of 2023 grew 10% year-over-year

May 3, 2023 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934. For the quarterly period ended March 31, 2023 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934. For the transition period from to Commission file number

April 28, 2023 DEF 14A

DEFINITIVE PROXY STATEMENT

.11 11 United Therapeutics C O R P O R A T I O N A Public Benefit Corporation Notice of Annual Meeting of Shareholders and Proxy Statement About United Therapeutics Our company was founded over 26 years ago with the challenge of finding a way to cure or treat a rare, life-threatening illness suffered by our CEO's daughter. That mission continues today, has grown to encompass a variety of rare dise

April 28, 2023 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) ☑ Filed by the Registrant ☐ Filed by a party other than the Registrant CHECK THE APPROPRIATE BOX: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14

April 28, 2023 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) ☑ Filed by the Registrant ☐ Filed by a party other than the Registrant CHECK THE APPROPRIATE BOX: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☐ Defin

April 21, 2023 EX-3.1

Tenth Amended and Restated Bylaws of the Registrant, incorporated by reference to Exhibit 3.1 of the Registrant’s Current Report on Form 8-K filed April 21, 2023

Exhibit 3.1 TENTH AMENDED AND RESTATED BYLAWS OF UNITED THERAPEUTICS CORPORATION (A PUBLIC BENEFIT CORPORATION) ARTICLE I OFFICES Section 1.1. Registered Office. The registered office of United Therapeutics Corporation, a public benefit corporation organized under the laws of the State of Delaware (the “Corporation”), shall be in the State of Delaware at such location and with such registered agen

April 21, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 20, 2023 United Therapeuti

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 20, 2023 United Therapeutics Corporation (Exact Name of Registrant as Specified in its Charter) Delaware 000-26301 52-1984749 (State or Other (Commission (I.R.S. Employer Juris

March 31, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 31, 2023 United Therapeuti

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 31, 2023 United Therapeutics Corporation (Exact Name of Registrant as Specified in its Charter) Delaware 000-26301 52-1984749 (State or Other (Commission (I.R.S. Employer Juris

February 22, 2023 EX-10.37

Form of Grant Notice and Standard Terms and Conditions for Stock Options Granted to Employees (Performance Vesting) under the United Therapeutics Corporation Amended and Restated 2015 Stock Incentive Plan (applicable to performance-based stock options granted on or after March 15, 2023)

Exhibit 10.37 UNITED THERAPEUTICS CORPORATION GRANT NOTICE FOR 2015 STOCK INCENTIVE PLAN NONQUALIFIED STOCK OPTIONS FOR EMPLOYEES (PERFORMANCE VESTING) FOR GOOD AND VALUABLE CONSIDERATION, United Therapeutics Corporation (the “Company”), hereby grants to Participant named below the nonqualified stock option (the “Option”) to purchase any part or all of the number of shares of its par value common

February 22, 2023 EX-10.38

Form of Grant Notice and Standard Terms and Conditions for Restricted Stock Units Granted to Employees (Performance Vesting) under the United Therapeutics Corporation Amended and Restated 2015 Stock Incentive Plan (applicable to performance-based restricted stock units granted on or after March 15, 2023)

Exhibit 10.38 UNITED THERAPEUTICS CORPORATION GRANT NOTICE FOR 2015 STOCK INCENTIVE PLAN RESTRICTED STOCK UNITS FOR EMPLOYEES (PERFORMANCE VESTING) FOR GOOD AND VALUABLE CONSIDERATION, United Therapeutics Corporation (the “Company”), hereby grants to Participant named below the restricted stock units (the “Award”) with respect to the number of shares of its par value common stock (the “Shares”), t

February 22, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 22, 2023 United Therape

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 22, 2023 United Therapeutics Corporation (Exact Name of Registrant as Specified in Charter) Delaware 000-26301 52-1984749 (State or Other Jurisdiction of Incorporation) (Com

February 22, 2023 EX-21

Subsidiaries of the Registrant.

Exhibit 21 SUBSIDIARIES OF THE REGISTRANT Lung Bioengineering Inc., a Delaware corporation Lung Biotechnology PBC, a Delaware public benefit corporation Revivicor, Inc., a Delaware corporation United Therapeutics Europe, Ltd., a company incorporated under the laws of England and Wales United Therapeutics Ireland Limited, a company incorporated under the laws of Ireland Unither Biotech Inc., a Cana

February 22, 2023 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K (Mark One) ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934. For the fiscal year ended December 31, 2022 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934. For the transition period from to Commission file number 0-26301 United Therapeu

February 22, 2023 EX-99.1

UNITED THERAPEUTICS CORPORATION REPORTS FOURTH QUARTER AND FULL YEAR 2022 FINANCIAL RESULTS

Exhibit 99.1 For Immediate Release UNITED THERAPEUTICS CORPORATION REPORTS FOURTH QUARTER AND FULL YEAR 2022 FINANCIAL RESULTS SILVER SPRING, Md. and RESEARCH TRIANGLE PARK, N.C., February 22, 2023: United Therapeutics Corporation (Nasdaq: UTHR), a public benefit corporation, today announced its financial results for the fourth quarter and year ended December 31, 2022. Full year total revenues ros

February 14, 2023 SC 13G/A

UTHR / United Therapeutics Corporation / Avoro Capital Advisors LLC - UNITED THERAPEUTICS CORPORATION Passive Investment

SC 13G/A 1 p23-0578sc13ga.htm UNITED THERAPEUTICS CORPORATION SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No. 2)* United Therapeutics Corporation (Name of Issuer) Common Stock, par value $0.01 per share (Title of Class of Securities) 91307C102 (CUSIP Number) December 31, 2022 (Date of Event Which Requires Filing of T

February 9, 2023 SC 13G/A

UTHR / United Therapeutics Corporation / VANGUARD GROUP INC - SCHEDULE 13G/A Passive Investment

SC 13G/A 1 tv02126-unitedtherapeuticsco.htm SCHEDULE 13G/A SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Schedule 13G Under the Securities Exchange Act of 1934 (Amendment No.: 10)* Name of issuer: United Therapeutics Corp. Title of Class of Securities: Common Stock CUSIP Number: 91307C102 Date of Event Which Requires Filing of this Statement: December 30, 2022 Check the appropriate box

February 6, 2023 SC 13G

UTHR / United Therapeutics Corporation / WELLINGTON MANAGEMENT GROUP LLP - SEC SCHEDULE 13G Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* United Therapeutics Corporation (Name of Issuer) Common Stock (Title of Class of Securities) 91307C102 (CUSIP Number) December 30, 2022 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to whi

February 6, 2023 SC 13G/A

CELU / Celularity Inc. Class A / UNITED THERAPEUTICS Corp - SC 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 13G (Rule 13d-102) Information to be Included in Statements Filed Pursuant to § 240.

February 3, 2023 SC 13G/A

CELU / Celularity Inc. Class A / UNITED THERAPEUTICS Corp - SC 13G/A Passive Investment

SC 13G/A 1 tm234873d1sc13g.htm SC 13G/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 13G (Rule 13d-102) Information to be Included in Statements Filed Pursuant to § 240.13d-1(b), (c) and (d) and Amendments Thereto Filed Pursuant to § 240.13d-2 Under the Securities Exchange Act of 1934 (Amendment No. 1) Celularity Operations Inc. (Name of Issuer) Common Stock, $0.0

February 3, 2023 SC 13G

CELU / Celularity Inc. Class A / UNITED THERAPEUTICS Corp - SCHEDULE 13G Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 13G (Rule 13d-102) Information to be Included in Statements Filed Pursuant to § 240.

February 2, 2023 SC 13G/A

VGG8959N1069 / Tottenham Acquisition I Limited / UNITED THERAPEUTICS Corp - SC 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 13G (Rule 13d-102) Information to be Included in Statements Filed Pursuant to § 240.

February 2, 2023 SC 13G/A

UTHR / United Therapeutics Corporation / ROTHBLATT MARTINE A - SC 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 13G (Rule 13d-102) Information to be Included in Statements Filed Pursuant to § 240.

January 17, 2023 SC 13G/A

VGG8959N1069 / Tottenham Acquisition I Limited / UNITED THERAPEUTICS Corp - SC 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 13G (Rule 13d-102) Information to be Included in Statements Filed Pursuant to § 240.

January 9, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 9, 2023 United Therapeut

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 9, 2023 United Therapeutics Corporation (Exact Name of Registrant as Specified in its Charter) Delaware 000-26301 52-1984749 (State or Other (Commission (I.R.S. Employer Juri

January 9, 2023 EX-99.1

UTHR: A Public Benefit Corporation | January 2023 | 1 United Therapeutics: Enabling Inspiration J.P. Morgan 41 st Annual Healthcare Conference

EX-99.1 2 tm232645d1ex99-1.htm EXHIBIT 99.1 Exhibit 99.1 UTHR: A Public Benefit Corporation | January 2023 | 1 United Therapeutics: Enabling Inspiration J.P. Morgan 41 st Annual Healthcare Conference UTHR: A Public Benefit Corporation | January 2023 | 2 Safe Harbor Statement This presentation contains forward - looking statements which represent United Therapeutics’ expectations or beliefs regardi

November 2, 2022 EX-99.1

United Therapeutics Corporation Reports Third Quarter 2022 Financial Results

Exhibit 99.1 For Immediate Release Contact: Dewey Steadman Phone: (202) 919-4097 Email: [email protected] United Therapeutics Corporation Reports Third Quarter 2022 Financial Results SILVER SPRING, Md. and RESEARCH TRIANGLE PARK, N.C., November 2, 2022: United Therapeutics Corporation (Nasdaq: UTHR), a public benefit corporation, today announced its financial results for the quarter ended September 3

November 2, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934. For the quarterly period ended September 30, 2022 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934. For the transition period from to Commission file num

November 2, 2022 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 2, 2022 United Therapeu

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 2, 2022 United Therapeutics Corporation (Exact Name of Registrant as Specified in Charter) Delaware 000-26301 52-1984749 (State or Other Jurisdiction of Incorporation) (Comm

October 11, 2022 EX-99.1

UNITED THERAPEUTICS ANNOUNCES FIRST PATIENT ENROLLED IN PHASE 3 TETON 2 STUDY OF TYVASO IN PATIENTS WITH IDIOPATHIC PULMONARY FIBROSIS Second registration study of Tyvaso® (treprostinil) Inhalation Solution for patients with IPF

Exhibit 99.1 For Immediate Release UNITED THERAPEUTICS ANNOUNCES FIRST PATIENT ENROLLED IN PHASE 3 TETON 2 STUDY OF TYVASO IN PATIENTS WITH IDIOPATHIC PULMONARY FIBROSIS Second registration study of Tyvaso® (treprostinil) Inhalation Solution for patients with IPF SILVER SPRING, Md. and RESEARCH TRIANGLE PARK, N.C., October 11, 2022: United Therapeutics Corporation (Nasdaq: UTHR), a public benefit

October 11, 2022 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 11, 2022 United Therapeu

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 11, 2022 United Therapeutics Corporation (Exact Name of Registrant as Specified in its Charter) Delaware 000-26301 52-1984749 (State or Other (Commission (I.R.S. Employer Jur

September 20, 2022 8-K

Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 20, 2022 United Therapeutics Corporation (Exact Name of Registrant as Specified in its Charter) Delaware 000-26301 52-1984749 (State or Other (Commission (I.R.S. Employer J

September 1, 2022 8-K

Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 31, 2022 United Therapeutics Corporation (Exact Name of Registrant as Specified in its Charter) Delaware 000-26301 52-1984749 (State or Other (Commission (I.R.S. Employer Juri

September 1, 2022 EX-99.1

United Therapeutics Prevails in Dry Powder Inhaler Patent Litigation

Exhibit 99.1 United Therapeutics Prevails in Dry Powder Inhaler Patent Litigation SILVER SPRING, Md., and RESEARCH TRIANGLE PARK, N.C., August 31, 2022 ? United Therapeutics Corporation (Nasdaq: UTHR), a public benefit corporation, announced today that the United States District Court for the District of Delaware issued an opinion in the pending litigation concerning United Therapeutics? U.S. pate

August 9, 2022 CORRESP

M e d i c i n e s   F o r   L i f e ®

1040 Spring Street Silver Spring, MD 20910 tel 301.608.9292 fax 301.608.9291 August 9, 2022 SUBMITTED VIA EDGAR Division of Corporate Finance Office of Life Sciences United States Securities and Exchange Commission 100 F Street, NE Washington, D.C. 20549 Attn: Christie Wong and Daniel Gordon Re: United Therapeutics Corporation Form 10-K for the Fiscal Year Ended December 31, 2021 Filed February 24

August 3, 2022 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 3, 2022 United Therapeutics Corporation (Exact Name of Registrant as Specified in Charter) Delaware 000-26301 52-1984749 (State or Other Jurisdiction of Incorporation) (Commis

August 3, 2022 EX-99.1

United Therapeutics Corporation Reports Second Quarter 2022 Financial Results

Exhibit 99.1 For Immediate Release Contact: Dewey Steadman Phone: (202) 919-4097 Email: [email protected] United Therapeutics Corporation Reports Second Quarter 2022 Financial Results SILVER SPRING, Md. and RESEARCH TRIANGLE PARK, N.C., August 3, 2022: United Therapeutics Corporation (Nasdaq: UTHR), a public benefit corporation, today announced its financial results for the quarter ended June 30, 202

August 3, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934. For the quarterly period ended June 30, 2022 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934. For the transition period from to Commission file number 0

August 3, 2022 EX-10.3

Second Amendment to Specialty Pharmacy Network Agreement, dated as of June 13, 2022, between the Registrant and Accredo Health Group, Inc., incorporated by reference to Exhibit 10.3 to the Registrant’s Quarterly Report on Form 10-Q for the quarter ended June 30, 2022.

Exhibit 10.3 SECOND AMENDMENT TO SPECIALTY PHARMACY NETWORK AGREEMENT This Second Amendment to Specialty Pharmacy Network Agreement (this “Amendment”) is made as of the date the last Party executes this Amendment (the “Amendment Effective Date”), by and between Accredo Health Group, Inc. (“Specialty Pharmacy”), and United Therapeutics Corporation (“UT”). Specialty Pharmacy and UT are each referred

August 3, 2022 EX-FILING FEES

Filing Fee Table*

EX-FILING FEES 4 tm2222193d1ex-filingfees.htm EX-FILING FEES Exhibit 107 CALCULATION OF FILING FEE TABLES Form S-8 (Form Type) United Therapeutics Corporation (Exact Name of Registrant as Specified in its Charter) TABLE 1 – NEWLY REGISTERED SECURITIES Security Type Security Class Title Fee Calculation Rule Amount Registered (1) Proposed Maximum Offering Price Per Unit Maximum Aggregate Offering Pr

August 3, 2022 EX-10.1

License and Collaboration Agreement, dated as of September 3, 2018, by and between the Registrant and MannKind Corporation, incorporated by reference to Exhibit 10.1 to the Registrant’s Quarterly Report on Form 10-Q, for the quarter ended June 30, 2022.

Certain information (marked as [***]) has been excluded from this exhibit because it is both (i) not material and (ii) would be competitively harmful if publicly disclosed.

August 3, 2022 S-8

As filed with the Securities and Exchange Commission on August 3, 2022

As filed with the Securities and Exchange Commission on August 3, 2022 Registration No.

June 28, 2022 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits, Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 27, 2022 United Therapeutics Corporation (Exact Name of Registrant as Specified in its Charter) Delaware 000-26301 52-1984749 (State or Other (Commission (I.R.S. Employer Jurisd

June 28, 2022 EX-10.1

United Therapeutics Corporation Amended and Restated 2015 Stock Incentive Plan

Exhibit 10.1 UNITED THERAPEUTICS CORPORATION AMENDED AND RESTATED 2015 STOCK INCENTIVE PLAN (effective June 27, 2022) 1. Purpose The purpose of the United Therapeutics Corporation Amended and Restated 2015 Stock Incentive Plan (this ?Plan?) is to advance the interests of United Therapeutics Corporation (the ?Company?) by stimulating the efforts of employees, officers, non-employee directors and ot

May 31, 2022 SD

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM SD SPECIALIZED DISCLOSURE REPORT United Therapeutics Corporation (Exact Name of Registrant as Specified in Charter)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM SD SPECIALIZED DISCLOSURE REPORT United Therapeutics Corporation (Exact Name of Registrant as Specified in Charter) Delaware 000-26301 52-1984749 (State or Other (Commission (I.R.S. Employer Jurisdiction of File Number) Identification Number) Incorporation or Organization) 1040 Spring Street Silver Spring, MD 20910 (Addre

May 24, 2022 EX-99.1

United Therapeutics Announces FDA Approval of Tyvaso DPI™ First approval of a dry powder inhaler for treatment of PAH and PH-ILD DPI device represents a convenient option for administration of treprostinil therapy Commercial launch activities underwa

Exhibit 99.1 United Therapeutics Announces FDA Approval of Tyvaso DPI? First approval of a dry powder inhaler for treatment of PAH and PH-ILD DPI device represents a convenient option for administration of treprostinil therapy Commercial launch activities underway; patient availability expected in June 2022 SILVER SPRING, Md., and RESEARCH TRIANGLE PARK, N.C., May 24, 2022 ? United Therapeutics Co

May 24, 2022 8-K

Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 23, 2022 United Therapeutics Corporation (Exact Name of Registrant as Specified in its Charter) Delaware 000-26301 52-1984749 (State or Other (Commission (I.R.S. Employer Jurisdi

May 4, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q (Mark One) ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934. For the quarterly period ended March 31, 2022 OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934. For the transition period from to Commission file number

May 4, 2022 EX-99.1

United Therapeutics Corporation Reports First Quarter 2022 Financial Results

Exhibit 99.1 For Immediate Release Contact: Dewey Steadman Phone: (202) 919-4097 Email: [email protected] United Therapeutics Corporation Reports First Quarter 2022 Financial Results SILVER SPRING, Md. and RESEARCH TRIANGLE PARK, N.C., May 4, 2022: United Therapeutics Corporation (Nasdaq: UTHR), a public benefit corporation, today announced its financial results for the quarter ended March 31, 2022.

May 4, 2022 EX-10.1

First Amendment to Specialty Pharmacy Network Agreement, dated as of February 16, 2022, between the Registrant and Accredo Health Group, Inc., incorporated by reference to Exhibit 10.1 to the Registrant’s Quarterly Report on Form 10-Q for the quarter ended March 31, 2022.

Exhibit 10.1 FIRST AMENDMENT TO SPECIALTY PHARMACY NETWORK AGREEMENT This First Amendment to Specialty Pharmacy Network Agreement (this ?Amendment?) is made as of the date the last Party executes this Amendment (the ?Amendment Effective Date?), by and between Accredo Health Group, Inc. (?Specialty Pharmacy?), and United Therapeutics Corporation (?UT?). Specialty Pharmacy and UT are each referred t

May 4, 2022 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 4, 2022 United Therapeutics Corporation (Exact Name of Registrant as Specified in Charter) Delaware 000-26301 52-1984749 (State or Other Jurisdiction of Incorporation) (Commissio

April 29, 2022 DEF 14A

DEFINITIVE PROXY STATEMENT

April 29, 2022 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ? Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confidential, for Use of the Commission Only (as permitted by Rule 14

April 29, 2022 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ? Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ? Defin

April 22, 2022 8-K

Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 21, 2022 United Therapeutics Corporation (Exact Name of Registrant as Specified in its Charter) Delaware 000-26301 52-1984749 (State or Other (Commission (I.R.S. Employer Juris

April 1, 2022 8-K

Entry into a Material Definitive Agreement, Termination of a Material Definitive Agreement, Financial Statements and Exhibits, Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 31, 2022 United Therapeutics Corporation (Exact Name of Registrant as Specified in its Charter) Delaware 000-26301 52-1984749 (State or Other (Commission (I.R.S. Employer Juris

April 1, 2022 EX-10.1

Credit Agreement, dated as of March 31, 2022, among the Registrant, certain of its subsidiaries party thereto, as guarantors, the lenders referred to therein, and Wells Fargo Bank, National Association, as administrative agent and as a swingline lender, incorporated by reference to Exhibit 10.1 to the Registrant's Current Report on Form 8-K filed on April 1, 2022.

? Exhibit 10.1 ? Execution Version ? ? ? $2,000,000,000 ? CREDIT AGREEMENT ? dated as of March 31, 2022 ? by and among ? UNITED THERAPEUTICS CORPORATION, as Borrower, ? CERTAIN SUBSIDIARIES OF THE BORROWER PARTY HERETO, as Guarantors, ? THE LENDERS REFERRED TO HEREIN, as Lenders, ? BANK OF AMERICA, N.A., DNB CAPITAL LLC, MUFG Bank, Ltd., and PNC BANK, NATIONAL ASSOCIATION, as co-Syndication Agents

February 24, 2022 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K (Mark One) ? ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934. For the fiscal year ended December 31, 2021 OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934. For the transition period from to Commission file number 0-26301 United Therapeu

February 24, 2022 EX-4.2

Act, incorporated by reference to Exhibit 4.2 to the Registrant’s Annual Report on Form 10-K for the year ended December 31, 2021.

Exhibit 4.2 DESCRIPTION OF THE REGISTRANT?S SECURITIES REGISTERED PURSUANT TO SECTION 12 OF THE SECURITIES EXCHANGE ACT OF 1934 United Therapeutics Corporation has one class of securities registered under Section 12 of the Securities Exchange Act of 1934, as amended (the Exchange Act): Common Stock, par value $0.01 per share (common stock). All references in this document to United Therapeutics, o

February 24, 2022 EX-99.1

United Therapeutics Corporation Reports Fourth Quarter and Full Year 2021 Financial Results Double-digit percentage revenue and patient count growth in full-year 2021 Company reaffirms target to reach 6,000 patients with Tyvaso by the end of 2022 Maj

Exhibit 99.1 For Immediate Release Contact: Dewey Steadman Phone: (202) 919-4097 Email: [email protected] United Therapeutics Corporation Reports Fourth Quarter and Full Year 2021 Financial Results Double-digit percentage revenue and patient count growth in full-year 2021 Company reaffirms target to reach 6,000 patients with Tyvaso by the end of 2022 Major amendment to Tyvaso DPI? NDA pushes FDA deci

February 24, 2022 EX-10.57

Ninth Amendment to Wholesale Product Purchase Agreement, dated as of October 6, 2021, by and between Priority Healthcare Distribution, Inc., doing business as CuraScript SD Specialty Distribution, and the Registrant, incorporated by reference to Exhibit 10.57 to the Registrant’s Annual Report on Form 10-K for the year ended December 31, 2021.

Exhibit 10.57 Ninth Amendment To Wholesale Product Purchase Agreement This Ninth Amendment to Wholesale Product Purchase Agreement (this ?Ninth Amendment? is made as of the date the last Party executes this Ninth Amendment (the ?Amendment Effective Date?), by and between Priority Healthcare Distribution, Inc., doing business as CuraScript SD Specialty Distribution, a Florida corporation having off

February 24, 2022 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 24, 2022 United Therapeutics Corporation (Exact Name of Registrant as Specified in Charter) Delaware 000-26301 52-1984749 (State or Other Jurisdiction of Incorporation) (Com

February 24, 2022 EX-21

Subsidiaries of the Registrant.

Exhibit 21 SUBSIDIARIES OF THE REGISTRANT Lung Bioengineering Inc., a Delaware corporation Lung Biotechnology PBC, a Delaware public benefit corporation Revivicor, Inc., a Delaware corporation United Therapeutics Europe, Ltd., a company incorporated under the laws of England and Wales Unither Biotech Inc., a Canadian company Unither Bioelectronics, Inc., a Canadian company Unither Pharma, LLC, a D

February 11, 2022 SC 13G/A

UTHR / United Therapeutics Corporation / Avoro Capital Advisors LLC - UNITED THERAPEUTICS CORPORATION Passive Investment

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No. 1)* United Therapeutics Corporation (Name of Issuer) Common Stock, par value $0.01 per share (Title of Class of Securities) 91307C102 (CUSIP Number) December 31, 2021 (Date of Event Which Requires Filing of This Statement) Check the appropriate box to designate the rule

February 10, 2022 SC 13G/A

UTHR / United Therapeutics Corporation / VANGUARD GROUP INC - SCHEDULE 13G/A Passive Investment

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Schedule 13G Under the Securities Exchange Act of 1934 (Amendment No.: 9)* Name of issuer: United Therapeutics Corp. Title of Class of Securities: Common Stock CUSIP Number: 91307C102 Date of Event Which Requires Filing of this Statement: December 31, 2021 Check the appropriate box to designate the rule pursuant to which this Schedule is fi

February 4, 2022 SC 13G/A

UTHR / United Therapeutics Corporation / ROTHBLATT MARTINE A - SCHEDULE 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 13G (Rule 13d-102) Information to be Included in Statements Filed Pursuant to ? 240.

February 4, 2022 SC 13G

CELU / Celularity Inc. Class A / UNITED THERAPEUTICS Corp - SCHEDULE 13G Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 13G (Rule 13d-102) Information to be Included in Statements Filed Pursuant to ? 240.

January 18, 2022 8-K

Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 18, 2022 United Therapeutics Corporation (Exact Name of Registrant as Specified in its Charter) Delaware 000-26301 52-1984749 (State or Other (Commission (I.R.S. Employer Jur

January 14, 2022 SC 13G/A

VGG8959N1069 / Tottenham Acquisition I Limited / UNITED THERAPEUTICS Corp - SCHEDULE 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 13G (Rule 13d-102) Information to be Included in Statements Filed Pursuant to ? 240.

December 27, 2021 8-K

Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 27, 2021 United Therapeutics Corporation (Exact Name of Registrant as Specified in its Charter) Delaware 000-26301 52-1984749 (State or Other (Commission (I.R.S. Employer Ju

November 3, 2021 EX-99.1

United Therapeutics Corporation Reports Third Quarter 2021 Financial Results

Exhibit 99.1 For Immediate Release Contact: Dewey Steadman Phone: (202) 919-4097 Email: [email protected] United Therapeutics Corporation Reports Third Quarter 2021 Financial Results SILVER SPRING, MD. and RESEARCH TRIANGLE PARK, N.C., November 3, 2021: United Therapeutics Corporation (Nasdaq: UTHR), a public benefit corporation with a purpose to provide a brighter future for patients, today announce

November 3, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 3, 2021 United Therapeutics Corporation (Exact Name of Registrant as Specified in Charter) Delaware 000-26301 52-1984749 (State or Other Jurisdiction of Incorporation) (Comm

November 3, 2021 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q (Mark One) ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934. For the quarterly period ended September 30, 2021 OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934. For the transition period from to Commission file num

October 18, 2021 8-K

Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 18, 2021 United Therapeutics Corporation (Exact Name of Registrant as Specified in its Charter) Delaware 000-26301 52-1984749 (State or Other (Commission (I.R.S. Employer Jur

October 18, 2021 EX-99.1

United Therapeutics Provides an Update on the Progress of the Tyvaso DPI™ New Drug Application Draft label contains both PAH and PH-ILD indications; no contraindications and no boxed warning Complete response cites an open inspection issue at a third

Exhibit 99.1 For Immediate Release United Therapeutics Provides an Update on the Progress of the Tyvaso DPI? New Drug Application Draft label contains both PAH and PH-ILD indications; no contraindications and no boxed warning Complete response cites an open inspection issue at a third-party analytical testing facility; no other deficiencies cited Approval and launch expected in summer 2022 or earl

October 1, 2021 8-K

Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year, Entry into a Material Definitive Agreement, Financial Statements and Exhibits, Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 30, 2021 United Therapeutics Corporation (Exact Name of Registrant as Specified in its Charter) Delaware 000-26301 52-1984749 (State or Other (Commission (I.R.S. Employer J

October 1, 2021 EX-10.1

Form of Indemnification Agreement between the Registrant and each of its Directors and Executive Officers, incorporated by reference to Exhibit 10.1 of the Registrant’s Current Report on Form 8-K filed October 1, 2021.

Exhibit 10.1 FORM OF INDEMNIFICATION AGREEMENT This Indemnification Agreement (this ?Agreement?), dated as of , is made by and between UNITED THERAPEUTICS CORPORATION, a Delaware public benefit corporation (the ?Company?), and (the ?Indemnitee?), an ?agent? (as hereinafter defined) of the Company. RECITALS A. The Company recognizes that competent and experienced persons are increasingly reluctant

October 1, 2021 EX-3.1

Restated Certificate of Incorporation of the Registrant, incorporated by reference to Exhibit 3.1 to the Registrant’s Current Report on Form 8-K filed October 1, 2021

Exhibit 3.1 RESTATED CERTIFICATE OF INCORPORATION OF UNITED THERAPEUTICS CORPORATION (A PUBLIC BENEFIT CORPORATION) It is hereby certified that: 1. The present name of the corporation (hereinafter called the ?corporation?) is United Therapeutics Corporation. The name under which the corporation was originally incorporated was Lung Rx, Inc.; and the date of filing the original certificate of incorp

September 10, 2021 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant x Filed by a Party other than the Registrant o Check the appropriate box: ? Preliminary Proxy Statement ? Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ? Defin

August 19, 2021 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) ? Filed by the Registrant ? Filed by a Party other than the Registrant CHECK THE APPROPRIATE BOX: ? Preliminary Proxy Statement ? Confidential, For Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ? Defin

August 19, 2021 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) ☑ Filed by the Registrant ☐ Filed by a Party other than the Registr

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) ? Filed by the Registrant ? Filed by a Party other than the Registrant CHECK THE APPROPRIATE BOX: ? Preliminary Proxy Statement ? Confidential, For Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ? Defin

August 19, 2021 DEF 14A

DEFINITIVE PROXY STATEMENT

August 4, 2021 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant x Filed by a Party other than the Registrant o Check the appropriate box: ? Preliminary Proxy Statement ? Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ? Defin

August 4, 2021 S-8

Form S-8 (No. 333-258434) filed with the Securities and Exchange Commission on August 4, 2021

As filed with the Securities and Exchange Commission on August 4, 2021 Registration No.

August 4, 2021 EX-99.1

United Therapeutics Corporation Reports Second Quarter 2021 Financial Results Tyvaso® (treprostinil) Inhalation Solution net revenue growth of 29% year over year; total net revenue growth of 23% year over year Tyvaso DPI™ NDA under review with FDA ac

Exhibit 99.1 For Immediate Release Contact: Dewey Steadman Phone: (202) 919-4097 Email: [email protected] United Therapeutics Corporation Reports Second Quarter 2021 Financial Results Tyvaso? (treprostinil) Inhalation Solution net revenue growth of 29% year over year; total net revenue growth of 23% year over year Tyvaso DPI? NDA under review with FDA action expected in October 2021 SILVER SPRING, MD

August 4, 2021 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q (Mark One) ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934. For the quarterly period ended June 30, 2021 OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934. For the transition period from to Commission file number 0

August 4, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 4, 2021 United Therapeutics Corporation (Exact Name of Registrant as Specified in Charter) Delaware 000-26301 52-1984749 (State or Other Jurisdiction of Incorporation) (Commis

July 14, 2021 PRE 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) ? Filed by the Registrant ? Filed by a Party other than the Registrant CHECK THE APPROPRIATE BOX: ? Preliminary Proxy Statement ? Confidential, For Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ? Defin

June 25, 2021 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits, Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 25, 2021 United Therapeutics Corporation (Exact Name of Registrant as Specified in its Charter) Delaware 000-26301 52-1984749 (State or Other (Commission (I.R.S. Employer Jurisd

June 25, 2021 EX-10.1

United Therapeutics Corporation Amended and Restated 2015 Stock Incentive Plan

Exhibit 10.1 UNITED THERAPEUTICS CORPORATION AMENDED AND RESTATED 2015 STOCK INCENTIVE PLAN (effective June 25, 2021) 1. Purpose The purpose of the United Therapeutics Corporation Amended and Restated 2015 Stock Incentive Plan (this ?Plan?) is to advance the interests of United Therapeutics Corporation (the ?Company?) by stimulating the efforts of employees, officers, non-employee directors and ot

June 23, 2021 8-K

Termination of a Material Definitive Agreement, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 22, 2021 United Therapeutics Corporation (Exact Name of Registrant as Specified in its Charter) Delaware 000-26301 52-1984749 (State or Other (Commission (I.R.S. Employer Jurisd

June 17, 2021 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant x Filed by a party other than the Registrant o Check the appropriate box: ? Preliminary Proxy Statement ? Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)

June 16, 2021 8-K

Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 16, 2021 United Therapeutics Corporation (Exact Name of Registrant as Specified in its Charter) Delaware 000-26301 52-1984749 (State or Other (Commission (I.R.S. Employer Jurisd

June 16, 2021 EX-99.1

UNITED THERAPEUTICS ANNOUNCES FDA ACCEPTANCE OF TYVASO DPI™ NEW DRUG APPLICATION FOR PRIORITY REVIEW FDA action expected in October 2021

Exhibit 99.1 For Immediate Release UNITED THERAPEUTICS ANNOUNCES FDA ACCEPTANCE OF TYVASO DPI? NEW DRUG APPLICATION FOR PRIORITY REVIEW FDA action expected in October 2021 SILVER SPRING, Md., and RESEARCH TRIANGLE PARK, N.C., Wednesday, June 16, 2021 ? United Therapeutics Corporation (Nasdaq: UTHR) today announced that the U.S. Food and Drug Administration (FDA) accepted for priority review the Ne

June 7, 2021 EX-99.1

UNITED THERAPEUTICS PURSUES NEW CLAIMS FOR TRADE SECRET MISAPPROPRIATION AGAINST LIQUIDIA

Exhibit 99.1 For Immediate Release UNITED THERAPEUTICS PURSUES NEW CLAIMS FOR TRADE SECRET MISAPPROPRIATION AGAINST LIQUIDIA SILVER SPRING, Md. and RESEARCH TRIANGLE PARK, N.C., Monday, June 7, 2021: United Therapeutics Corporation (Nasdaq: UTHR) announced today that it is pursuing additional claims for trade secret misappropriation against Liquidia Technologies, Inc. (a subsidiary of Liquidia Cor

June 7, 2021 8-K

Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 7, 2021 United Therapeutics Corporation (Exact Name of Registrant as Specified in its Charter) Delaware 000-26301 52-1984749 (State or Other (Commission (I.R.S. Employer Jurisdi

June 3, 2021 EX-99.1

UNITED THERAPEUTICS ANNOUNCES FIRST PATIENT ENROLLED IN PHASE 3 TETON STUDY OF TYVASO IN PATIENTS WITH IDIOPATHIC PULMONARY FIBROSIS First pivotal study of Tyvaso® (treprostinil) Inhalation Solution outside pulmonary hypertension

Exhibit 99.1 For Immediate Release UNITED THERAPEUTICS ANNOUNCES FIRST PATIENT ENROLLED IN PHASE 3 TETON STUDY OF TYVASO IN PATIENTS WITH IDIOPATHIC PULMONARY FIBROSIS First pivotal study of Tyvaso? (treprostinil) Inhalation Solution outside pulmonary hypertension SILVER SPRING, Md. and RESEARCH TRIANGLE PARK, N.C., Thursday, June 3, 2021: United Therapeutics Corporation (Nasdaq: UTHR) announced t

June 3, 2021 8-K

Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 3, 2021 United Therapeutics Corporation (Exact Name of Registrant as Specified in its Charter) Delaware 000-26301 52-1984749 (State or Other (Commission (I.R.S. Employer Jurisdi

June 1, 2021 SD

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM SD SPECIALIZED DISCLOSURE REPORT United Therapeutics Corporation (Exact Name of Registrant as Specified in Charter)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM SD SPECIALIZED DISCLOSURE REPORT United Therapeutics Corporation (Exact Name of Registrant as Specified in Charter) Delaware 000-26301 52-1984749 (State or Other (Commission (I.R.S. Employer Jurisdiction of File Number) Identification Number) Incorporation or Organization) 1040 Spring Street Silver Spring, MD 20910 (Addre

May 5, 2021 10-Q

Quarterly Report - 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q (Mark One) ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934. For the quarterly period ended March 31, 2021 OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934. For the transition period from to Commission file number

May 5, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 5, 2021 United Therapeutics Corporation (Exact Name of Registrant as Specified in Charter) Delaware 000-26301 52-1984749 (State or Other Jurisdiction of Incorporation) (Commissio

May 5, 2021 EX-99.1

United Therapeutics Corporation Reports First Quarter 2021 Financial Results Tyvaso® (treprostinil) Inhalation Solution approved for pulmonary hypertension associated with interstitial lung disease (PH-ILD) Tyvaso DPI™ New Drug Application (NDA) subm

Exhibit 99.1 For Immediate Release Contact: Dewey Steadman Phone: (202) 919-4097 Email: [email protected] United Therapeutics Corporation Reports First Quarter 2021 Financial Results Tyvaso? (treprostinil) Inhalation Solution approved for pulmonary hypertension associated with interstitial lung disease (PH-ILD) Tyvaso DPI? New Drug Application (NDA) submitted to U.S. Food and Drug Administration TETO

April 29, 2021 DEFA14A

- DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant x Filed by a Party other than the Registrant o Check the appropriate box: ? Preliminary Proxy Statement ? Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ? Defin

April 29, 2021 DEFA14A

- DEFINITIVE ADDITIONAL PROXY SOLICITING MATERIALS

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ? Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ? Defin

April 29, 2021 DEF 14A

DEFINITIVE PROXY STATEMENT

April 29, 2021 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registran

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ? Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confidential, for Use of the Commission Only (as permitted by Rule 14

April 19, 2021 EX-99.1

UNITED THERAPEUTICS ANNOUNCES SUBMISSION OF TYVASO DPI™ NEW DRUG APPLICATION TO FDA NDA submission includes both pulmonary arterial hypertension and pulmonary hypertension associated with interstitial lung disease indications Priority review voucher

Exhibit 99.1 For Immediate Release UNITED THERAPEUTICS ANNOUNCES SUBMISSION OF TYVASO DPI™ NEW DRUG APPLICATION TO FDA NDA submission includes both pulmonary arterial hypertension and pulmonary hypertension associated with interstitial lung disease indications Priority review voucher applied to the NDA submission SILVER SPRING, Md. and RESEARCH TRIANGLE PARK, N.C., Monday, April 19, 2021: United T

April 19, 2021 8-K

Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 19, 2021 United Therapeutics Corporation (Exact Name of Registrant as Specified in its Charter) Delaware 000-26301 52-1984749 (State or Other (Commission (I.R.S. Employer Juris

April 1, 2021 EX-99.1

United Therapeutics Announces FDA Approval and Launch of Tyvaso® for the Treatment of Pulmonary Hypertension Associated with Interstitial Lung Disease First and only approved therapy in the United States for patients with PH-ILD, a serious, life-thre

Exhibit 99.1 For Immediate Release United Therapeutics Announces FDA Approval and Launch of Tyvaso® for the Treatment of Pulmonary Hypertension Associated with Interstitial Lung Disease First and only approved therapy in the United States for patients with PH-ILD, a serious, life-threatening disease with potentially more than 30,000 patients in need FDA approval based on data from the INCREASE cli

April 1, 2021 8-K

Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 1, 2021 United Therapeutics Corporation (Exact Name of Registrant as Specified in its Charter) Delaware 000-26301 52-1984749 (State or Other (Commission (I.R.S. Employer Jurisd

March 3, 2021 8-K

Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 2, 2021 United Therapeutics Corporation (Exact Name of Registrant as Specified in its Charter) Delaware 000-26301 52-1984749 (State or Other (Commission (I.R.S. Employer Jurisd

March 1, 2021 SC 13G/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 13G (Rule 13d-102) Information to be Included in Statements Filed Pursuant to § 240.13d-1(b), (c) and (d) and Amendments Thereto Filed Pursuant to § 240.13d-2 Under the Se

SC 13G/A 1 tm218268d1sc13ga.htm SCHEDULE 13G/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 13G (Rule 13d-102) Information to be Included in Statements Filed Pursuant to § 240.13d-1(b), (c) and (d) and Amendments Thereto Filed Pursuant to § 240.13d-2 Under the Securities Exchange Act of 1934 (Amendment No. ) United Therapeutics Corporation (Name of Issuer) Common

February 24, 2021 EX-4.2

Description of Securities Registered under Section 12 of the Exchange

Exhibit 4.2 DESCRIPTION OF THE REGISTRANT?S SECURITIES REGISTERED PURSUANT TO SECTION 12 OF THE SECURITIES EXCHANGE ACT OF 1934 United Therapeutics Corporation (?United Therapeutics?) has one class of securities registered under Section 12 of the Securities Exchange Act of 1934, as amended (the ?Exchange Act?): our Common Stock, par value $0.01 per share (our ?common stock?). DESCRIPTION OF COMMON

February 24, 2021 EX-99.1

UNITED THERAPEUTICS CORPORATION REPORTS FOURTH QUARTER AND FULL YEAR 2020 FINANCIAL RESULTS

Exhibit 99.1 For Immediate Release Contact: Dewey Steadman Phone: (202) 919-4097 Email: [email protected] UNITED THERAPEUTICS CORPORATION REPORTS FOURTH QUARTER AND FULL YEAR 2020 FINANCIAL RESULTS Silver Spring, MD and Research Triangle Park, NC, February 24, 2021: United Therapeutics Corporation (Nasdaq: UTHR) today announced its financial results for the fourth quarter and year ended December 31,

February 24, 2021 10-K

Annual Report - 10-K

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-K (Mark One) ? ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934. For the fiscal year ended December 31, 2020 OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934. For the transition period from to Commission file number 0-263

February 24, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 24, 2021 United Therapeutics Corporation (Exact Name of Registrant as Specified in Charter) Delaware 000-26301 52-1984749 (State or Other Jurisdiction of Incorporation) (Com

February 24, 2021 EX-21

Subsidiaries of the Registrant.

Exhibit 21 SUBSIDIARIES OF THE REGISTRANT Lung Bioengineering Inc., a Delaware corporation Lung Biotechnology PBC, a Delaware public benefit corporation Revivicor, Inc., a Delaware corporation SteadyMed Ltd., an Israeli company SteadyMed Therapeutics, Inc., a Delaware corporation United Therapeutics Europe, Ltd., a company incorporated under the laws of England and Wales Unither Biotech Inc., a Ca

February 12, 2021 SC 13G

United Therapeutics Corporation

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* United Therapeutics Corporation (Name of Issuer) Common Stock, par value $0.01 per share (Title of Class of Securities) 91307C102 (CUSIP Number) December 31, 2020 (Date of Event Which Requires Filing of This Statement) Check the appropriate box to designate the rule pu

February 10, 2021 8-K

Financial Statements and Exhibits, Other Events - FORM 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 10, 2021 United Therapeutics Corporation (Exact Name of Registrant as Specified in its Charter) Delaware 000-26301 52-1984749 (State or Other (Commission (I.R.S. Employer Ju

February 10, 2021 SC 13G/A

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Schedule 13G Under the Securities Exchange Act of 1934 (Amendment No.: 8)*

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Schedule 13G Under the Securities Exchange Act of 1934 (Amendment No.: 8)* Name of issuer: United Therapeutics Corp. Title of Class of Securities: Common Stock CUSIP Number: 91307C102 Date of Event Which Requires Filing of this Statement: December 31, 2020 Check the appropriate box to designate the rule pursuant to which this Schedule is fi

February 10, 2021 EX-99.1

UNITED THERAPEUTICS ANNOUNCES COMMERCIAL LAUNCH OF THE REMUNITY® PUMP FOR REMODULIN®

Exhibit 99.1 For Immediate Release UNITED THERAPEUTICS ANNOUNCES COMMERCIAL LAUNCH OF THE REMUNITY® PUMP FOR REMODULIN® SILVER SPRING, Md. and RESEARCH TRIANGLE PARK, N.C., Wednesday, February 10, 2021: United Therapeutics Corporation (Nasdaq: UTHR) announced today that it has launched commercial sales of the innovative Remunity® Pump for Remodulin® for patients with pulmonary arterial hypertensio

February 5, 2021 8-K

Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year, Financial Statements and Exhibits - FORM 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 4, 2021 United Therapeutics Corporation (Exact Name of Registrant as Specified in its Charter) Delaware 000-26301 52-1984749 (State or Other (Commission (I.R.S. Employer Jur

February 5, 2021 SC 13G/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 13G (Rule 13d-102) Information to be Included in Statements Filed Pursuant to § 240.13d-1(b), (c) and (d) and Amendments Thereto Filed Pursuant to § 240.13d-2 Under the Se

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 13G (Rule 13d-102) Information to be Included in Statements Filed Pursuant to § 240.

February 5, 2021 EX-3.1

Ninth Amended and Restated Bylaws of the Registrant, incorporated by reference to Exhibit 3.1 of the Registrant’s Current Report on Form 8-K filed February 5, 2021.

Exhibit 3.1 NINTH AMENDED AND RESTATED BYLAWS OF UNITED THERAPEUTICS CORPORATION ARTICLE I OFFICES Section 1.1. Registered Office. The registered office of United Therapeutics Corporation (the “Corporation”) shall be in the State of Delaware at such location and with such registered agent in charge thereof as may be established by the Board of Directors from time to time. Section 1.2. Other Office

January 28, 2021 8-K

Financial Statements and Exhibits, Other Events - FORM 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 28, 2021 United Therapeutics Corporation (Exact Name of Registrant as Specified in its Charter) Delaware 000-26301 52-1984749 (State or Other (Commission (I.R.S. Employer Jur

January 28, 2021 EX-99.1

UNITED THERAPEUTICS ANNOUNCES BREEZE STUDY OF INVESTIGATIONAL TYVASO DPI™ MEETS PRIMARY OBJECTIVE Study demonstrated safety and tolerability of Tyvaso DPI™ in patients with PAH transitioning from Tyvaso® Inhalation Solution A separate study in health

Exhibit 99.1 UNITED THERAPEUTICS ANNOUNCES BREEZE STUDY OF INVESTIGATIONAL TYVASO DPI™ MEETS PRIMARY OBJECTIVE Study demonstrated safety and tolerability of Tyvaso DPI™ in patients with PAH transitioning from Tyvaso® Inhalation Solution A separate study in healthy volunteers demonstrated comparable treprostinil exposure between Tyvaso DPI and Tyvaso Inhalation Solution Tyvaso DPI NDA filing antici

January 22, 2021 8-K

Other Events - FORM 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 21, 2021 United Therapeutics Corporation (Exact Name of Registrant as Specified in its Charter) Delaware 000-26301 52-1984749 (State or Other (Commission (I.R.S. Employer Jur

January 13, 2021 EX-99.1

United Therapeutics Announces New England Journal of Medicine Publication of the INCREASE Study Evaluating Tyvaso® in Pulmonary Hypertension Associated with Interstitial Lung Disease INCREASE Study is First to Demonstrate a Clear Benefit in Patients

Exhibit 99.1 For Immediate Release United Therapeutics Announces New England Journal of Medicine Publication of the INCREASE Study Evaluating Tyvaso® in Pulmonary Hypertension Associated with Interstitial Lung Disease INCREASE Study is First to Demonstrate a Clear Benefit in Patients with PH-ILD, a Life-threatening Disease with No Currently FDA-Approved Treatments Company to host a webcast detaili

January 13, 2021 8-K

Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 13, 2021 United Therapeutics Corporation (Exact Name of Registrant as Specified in its Charter) Delaware 000-26301 52-1984749 (State or Other (Commission (I.R.S. Employer Jur

January 8, 2021 SC 13G

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 13G (Rule 13d-102) Information to be Included in Statements Filed Pursuant to § 240.13d-1(b), (c) and (d) and Amendments Thereto Filed Pursuant to § 240.13d-2 Under the Se

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 13G (Rule 13d-102) Information to be Included in Statements Filed Pursuant to § 240.

December 28, 2020 8-K

Financial Statements and Exhibits, Other Events - FORM 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 28, 2020 United Therapeutics Corporation (Exact Name of Registrant as Specified in its Charter) Delaware 000-26301 52-1984749 (State or Other (Commission (I.R.S. Employer Ju

December 28, 2020 EX-99.1

UNITED THERAPEUTICS ANNOUNCES AGREEMENT TO ACQUIRE PRIORITY REVIEW VOUCHER Voucher expected to be applied to the forthcoming NDA for Tyvaso DPI™

Exhibit 99.1 For Immediate Release UNITED THERAPEUTICS ANNOUNCES AGREEMENT TO ACQUIRE PRIORITY REVIEW VOUCHER Voucher expected to be applied to the forthcoming NDA for Tyvaso DPI™ SILVER SPRING, Md. and RESEARCH TRIANGLE PARK, N.C., Monday, December 28, 2020: United Therapeutics Corporation (Nasdaq: UTHR) announced today an agreement to acquire a Rare Pediatric Disease Priority Review Voucher (PRV

December 23, 2020 CORRESP

* * *

1735 Connecticut Ave., NW Washington, DC 20009 tel 202.483.7000 fax 202.483.4005 December 23, 2020 SUBMITTED VIA EDGAR Office of Life Sciences Division of Corporation Finance United States Securities and Exchange Commission Washington, D.C. 20549 Attention: Dorrie Yale Suzanne Hayes Li Xiao Brian Cascio Re: United Therapeutics Corporation Form 10-K for the Fiscal Year Ended December 31, 2020 Filed

December 9, 2020 8-K

Financial Statements and Exhibits, Other Events - FORM 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15 (d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 9, 2020 United Therapeutics Corporation (Exact Name of Registrant as Specified in its Charter) Delaware 000-26301 52-1984749 (State or Other (Commission (I.R.S. Employer Jur

December 9, 2020 EX-99.1

United Therapeutics Receives FDA Orphan Drug Designation for TREPROSTINIL for the Treatment of Idiopathic Pulmonary Fibrosis Phase 3 TETON study planned in 2021 for Tyvaso® in patients with idiopathic pulmonary fibrosis

Exhibit 99.1 For Immediate Release For Further Information Contact: Dewey Steadman at (202) 919-4097 Email: [email protected] United Therapeutics Receives FDA Orphan Drug Designation for TREPROSTINIL for the Treatment of Idiopathic Pulmonary Fibrosis Phase 3 TETON study planned in 2021 for Tyvaso® in patients with idiopathic pulmonary fibrosis SILVER SPRING, Md. and RESEARCH TRIANGLE PARK, N.C., Wedn

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